UniProt Accession

 ACTY_HUMAN; P42025; D3DVH2; Q53SK5; Q9BRB7 

Genbank Protein ID

 X82207; AC017099; CH471127; CH471127; BC004374; BC006372; BC010090 

Genbank Nucleotide ID

 CAA57691.1; AAY24280.1; EAX01924.1; EAX01927.1; AAH04374.1; AAH06372.1; AAH10090.1 

Protein Name

 Beta-centractin 

Protein Synonyms/Alias

 Actin-related protein 1B; ARP1B 

Gene Name

 ACTR1B 

Gene Synonyms/Alias

 CTRN2 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
32	FAGDQIPKYCFPNYV	ubiquitination	[1, 2]
61	GDLFIGPKAEEHRGL	ubiquitination	[1, 2, 3]
119	EAPLNPSKNREKAAE	ubiquitination	[1]
319	DRLLSEVKKLAPKDI	ubiquitination	[1]
320	RLLSEVKKLAPKDIK	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

 Component of a multi-subunit complex involved in microtubule based vesicle motility. It is associated with the centrosome. 

Sequence Annotation

 MOD_RES 1 1 N-acetylmethionine.
 MOD_RES 4 4 Nitrated tyrosine (By similarity).  

Keyword

 Acetylation; ATP-binding; Complete proteome; Cytoplasm; Cytoskeleton; Direct protein sequencing; Nitration; Nucleotide-binding; Polymorphism; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 376 AA 

Protein Sequence

Gene Ontology

 GO:0005813; C:centrosome; IDA:UniProtKB.
 GO:0005829; C:cytosol; TAS:Reactome.
 GO:0005869; C:dynactin complex; TAS:ProtInc.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0019886; P:antigen processing and presentation of exogenous peptide antigen via MHC class II; TAS:Reactome. 

Interpro

 IPR004000; Actin-related.
 IPR020902; Actin/actin-like_CS.
 IPR004001; Actin_CS. 

Pfam

 PF00022; Actin 

SMART

 SM00268; ACTIN 

PROSITE

 PS00432; ACTINS_2
 PS01132; ACTINS_ACT_LIKE 

PRINTS

 PR00190; ACTIN.