CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021182
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transmembrane protein 39B 
Protein Synonyms/Alias
  
Gene Name
 TMEM39B 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
213QLNCDLRKTSLFNHMubiquitination[1]
234EAVSGLAKSRDYLLTubiquitination[1]
475RDRLVLGKAYSYSASubiquitination[2, 3]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789
Functional Description
  
Sequence Annotation
 CARBOHYD 8 8 N-linked (GlcNAc...) (Potential).  
Keyword
 Complete proteome; Glycoprotein; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 492 AA 
Protein Sequence
MGGRRGPNRT SYCRNPLCEP GSSGGSSGSH TSSASVTSVR SRTRSSSGTG LSSPPLATQT 60
VVPLQHCKIP ELPVQASILF ELQLFFCQLI ALFVHYINIY KTVWWYPPSH PPSHTSLNFH 120
LIDFNLLMVT TIVLGRRFIG SIVKEASQRG KVSLFRSILL FLTRFTVLTA TGWSLCRSLI 180
HLFRTYSFLN LLFLCYPFGM YIPFLQLNCD LRKTSLFNHM ASMGPREAVS GLAKSRDYLL 240
TLRETWKQHT RQLYGPDAMP THACCLSPSL IRSEVEFLKM DFNWRMKEVL VSSMLSAYYV 300
AFVPVWFVKN THYYDKRWSC ELFLLVSIST SVILMQHLLP ASYCDLLHKA AAHLGCWQKV 360
DPALCSNVLQ HPWTEECMWP QGVLVKHSKN VYKAVGHYNV AIPSDVSHFR FHFFFSKPLR 420
ILNILLLLEG AVIVYQLYSL MSSEKWHQTI SLALILFSNY YAFFKLLRDR LVLGKAYSYS 480
ASPQRDLDHR FS 492 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 
Interpro
 IPR019397; Uncharacterised_TMEM39. 
Pfam
 PF10271; Tmp39 
SMART
  
PROSITE
  
PRINTS