UniProt Accession

 GRPE_DROME; P48604; Q8SX27; Q9V6R8 

Genbank Protein ID

 U34903; AE013599; AY094889 

Genbank Nucleotide ID

 AAA79044.1; AAF58354.1; AAM11242.1 

Protein Name

 GrpE protein homolog, mitochondrial 

Protein Synonyms/Alias

 dRoe1 

Gene Name

 Roe1 

Gene Synonyms/Alias

 CG6155 

Created Date

 July 27, 2013 

Organism

 Drosophila melanogaster (Fruit fly) 

NCBI Taxa ID

 7227 

Lysine Modification

Position	Peptide	Type	References
57	ESSPEVEKLTKELAA	acetylation	[1]
60	PEVEKLTKELAAAKE	acetylation	[1]
75	QNAELMDKYKRSLAD	acetylation	[1]

Reference

 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 

Functional Description

 Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. Seems to control the nucleotide-dependent binding of mitochondrial HSP70 to substrate proteins (By similarity). 

Sequence Annotation

  

Keyword

 Chaperone; Complete proteome; Mitochondrion; Reference proteome; Transit peptide. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 213 AA 

Protein Sequence

Gene Ontology

 GO:0005759; C:mitochondrial matrix; IEA:UniProtKB-SubCell.
 GO:0000774; F:adenyl-nucleotide exchange factor activity; IEA:InterPro.
 GO:0022008; P:neurogenesis; IMP:FlyBase.
 GO:0006457; P:protein folding; IEA:InterPro. 

Interpro

 IPR000740; GrpE.
 IPR013805; GrpE_coiled_coil.
 IPR009012; GrpE_head. 

Pfam

 PF01025; GrpE 

SMART

  

PROSITE

 PS01071; GRPE 

PRINTS

 PR00773; GRPEPROTEIN.