CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025682
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 RNA binding protein (Autoantigenic, hnRNP-associated with lethal yellow) long isoform variant 
Protein Synonyms/Alias
 RNA binding protein, autoantigenic (HnRNP-associated with lethal yellow homolog (Mouse)); RNA binding protein, autoantigenic (HnRNP-associated with lethal yellow homolog (Mouse)), isoform CRA_a; cDNA FLJ77422, highly similar to Homo sapiens RNA binding protein, autoantigenic (hnRNP-associated with lethal yellow homolog (mouse)), transcript variant 1, mRNA 
Gene Name
 RALY 
Gene Synonyms/Alias
 hCG_37136 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
4****MSLKLQASNVTubiquitination[1, 2]
13QASNVTNKNDPKSINubiquitination[1]
34NLNTALVKKSDVETIubiquitination[1, 2]
44DVETIFSKYGRVAGCubiquitination[1, 2]
165VKTNVPVKLFARSTAubiquitination[1, 2]
183SSAKIKLKSSELQAIubiquitination[1]
191SSELQAIKTELTQIKubiquitination[1, 2]
198KTELTQIKSNIDALLubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965]
 [2] hCKSAAP_UbSite: improved prediction of human ubiquitination sites by exploiting amino acid pattern and properties.
 Chen Z, Zhou Y, Song J, Zhang Z.
 Biochim Biophys Acta. 2013 Aug;1834(8):1461-7. [PMID: 23603789
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 307 AA 
Protein Sequence
MSLKLQASNV TNKNDPKSIN SRVFIGNLNT ALVKKSDVET IFSKYGRVAG CSVHKGYAFV 60
QYSNERHARA AVLGENGRVL AGQTLDINMA GEPKPDRPKG LKRAASAIYS GYIFDYDYYR 120
DDFYDRLFDY RGRLSPVPVP RAVPVKRPRV TVPLVRRVKT NVPVKLFARS TAVTTSSAKI 180
KLKSSELQAI KTELTQIKSN IDALLSRLEQ IAAEQKANPD GKKKGDGGGA SGGGGGGGGS 240
GGGGSGGGGG GGSSRPPAPQ ENTTSEAGLP QGEARTRDDG DEEGLLTHSE EELEHSQDTD 300
ADDGALQ 307 
Gene Ontology
 GO:0003676; F:nucleic acid binding; IEA:InterPro.
 GO:0000166; F:nucleotide binding; IEA:InterPro. 
Interpro
 IPR017347; hnRNP_C_Raly.
 IPR012677; Nucleotide-bd_a/b_plait.
 IPR000504; RRM_dom. 
Pfam
 PF00076; RRM_1 
SMART
 SM00360; RRM 
PROSITE
 PS50102; RRM 
PRINTS