| Tag | Content |
|---|
| CPLM ID | CPLM-006144 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Beta-glucan synthesis-associated protein KRE6 |
Protein Synonyms/Alias | Killer toxin-resistance protein 6 |
Gene Name | KRE6 |
Gene Synonyms/Alias | CWH48; YPR159W |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 98 | RLDLSQNKGVSDYKG | ubiquitination | [1] | | 104 | NKGVSDYKGYYSRNN | ubiquitination | [1] | | 316 | PDTPDTAKTREAMDG | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Involved in the synthesis of (1->6)- and (1->3)-beta-D- glucan polymers of the yeast cell wall in vivo. It is required for full activity of beta-glucan synthase in vitro. May be involved in the maturation and transport of cell wall proteins (CWP) to the cell wall. May act as a transglucosidase and contribute to the construction of a protein-bound glucan-structure that acts as an acceptor site for the addition of (1->6)-beta-D-glucan at the cell surface. |
Sequence Annotation | MOD_RES 81 81 Phosphoserine.
MOD_RES 116 116 Phosphoserine.
MOD_RES 133 133 Phosphoserine.
MOD_RES 134 134 Phosphoserine.
MOD_RES 136 136 Phosphoserine.
MOD_RES 139 139 Phosphoserine.
CARBOHYD 374 374 N-linked (GlcNAc...) (Potential).
CARBOHYD 461 461 N-linked (GlcNAc...) (Potential).
CARBOHYD 538 538 N-linked (GlcNAc...) (Potential).
CARBOHYD 563 563 N-linked (GlcNAc...) (Potential).
CARBOHYD 691 691 N-linked (GlcNAc...) (Potential). |
Keyword | Cell wall biogenesis/degradation; Complete proteome; Glycoprotein; Golgi apparatus; Membrane; Phosphoprotein; Reference proteome; Signal-anchor; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 720 AA |
Protein Sequence | MPLRNLTETH NFSSTNLDTD GTGDDHDGAP LSSSPSFGQQ NDNSTNDNAG LTNPFMGSDE 60
ESNARDGESL SSSVHYQPQG SDSSLLHDNS RLDLSQNKGV SDYKGYYSRN NSRAVSTAND 120
NSFLQPPHRA IASSPSLNSN LSKNDILSPP EFDRYPLVGS RVTSMTQLNH HGRSPTSSPG 180
NESSASFSSN PFLGEQDFSP FGGYPASSFP LMIDEKEEDD YLHNPDPEEE ARLDRRRFID 240
DFKYMDKRSA SGLAGVLLLF LAAIFIFIVL PALTFTGAID HESNTEEVTY LTQYQYPQLS 300
AIRTSLVDPD TPDTAKTREA MDGSKWELVF SDEFNAEGRT FYDGDDPYWT APDVHYDATK 360
DLEWYSPDAS TTVNGTLQLR MDAFKNHGLY YRSGMLQSWN KVCFTQGALE ISANLPNYGR 420
VSGLWPGLWT MGNLGRPGYL ASTQGVWPYS YESCDAGITP NQSSPDGISY LPGQKLSICT 480
CDGEDHPNQG VGRGAPEIDV LEGETDTKIG VGIASQSLQI APFDIWYMPD YDFIEVYNFT 540
TTTMNTYAGG PFQQAVSAVS TLNVTWYEFG EYGGYFQKYA IEYLNDDDNG YIRWFVGDTP 600
TYTIHAKALH PDGNIGWRRI SKEPMSIILN LGISNNWAYI DWQYIFFPVV MSIDYVRIYQ 660
PSNAISVTCD PSDYPTYDYI QSHLNAFQNA NLTTWEDAGY TFPKNILTGK CTSSKFKLSS 720 |
Gene Ontology | GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell. GO:0030176; C:integral to endoplasmic reticulum membrane; IDA:SGD. GO:0005886; C:plasma membrane; IDA:SGD. GO:0030427; C:site of polarized growth; IDA:SGD. GO:0030133; C:transport vesicle; IDA:SGD. GO:0015926; F:glucosidase activity; IMP:SGD. GO:0006078; P:(1->6)-beta-D-glucan biosynthetic process; IMP:SGD. GO:0031505; P:fungal-type cell wall organization; IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |