CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027059
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 CG5261, isoform A 
Protein Synonyms/Alias
  
Gene Name
 CG5261, Dmel_CG5261 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
312KGVLEISKDVKALAAacetylation[1]
378VADPDSLKGFKEVNMacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702] 
Functional Description
  
Sequence Annotation
  
Keyword
 Acyltransferase; Complete proteome; Lipoyl; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 421 AA 
Protein Sequence
MERGSIVSWE KKEGDKLNEG DLLCEIETDK ATMGFETPEE GFLAKILIQG GTKDVPVGQL 60
LCIIVPDQGS VAAFANFKDD GAAAAPAAPA AAPAPAPAAA AAPPPPPPPA AAPAAAAPPP 120
APAAAPAAAG TGRVYASPMA KRLAEAQQLR LQGKGSGVHG SIKSGDLAGQ KAAAKPAAAA 180
PAKAPRAAGA RYEDIPVTNM RAVIAKRLLE SKTQLPHYYV TVQCQVDKLL KFRAKVNKKY 240
EKQGARVSVN DFIIKAVAIA SLKVPEANSA WMDTVIRKYD DVDVSVAVST DKGLITPIVF 300
NADRKGVLEI SKDVKALAAK ARDNKLQPHE FQGGTISVSN LGMFGVNQFA AVINPPQSCI 360
LAIGTTTKQL VADPDSLKGF KEVNMLTVTL SADHRVVDGA VAARWLQHFR DYMEDPSNMV 420
L 421 
Gene Ontology
 GO:0005811; C:lipid particle; IDA:FlyBase.
 GO:0045254; C:pyruvate dehydrogenase complex; IEA:InterPro.
 GO:0004742; F:dihydrolipoyllysine-residue acetyltransferase activity; IEA:EC.
 GO:0006090; P:pyruvate metabolic process; IEA:InterPro. 
Interpro
 IPR003016; 2-oxoA_DH_lipoyl-BS.
 IPR001078; 2-oxoacid_DH_actylTfrase.
 IPR000089; Biotin_lipoyl.
 IPR023213; CAT-like_dom.
 IPR004167; E3-bd.
 IPR006257; LAT1.
 IPR011053; Single_hybrid_motif. 
Pfam
 PF00198; 2-oxoacid_dh
 PF00364; Biotin_lipoyl
 PF02817; E3_binding 
SMART
  
PROSITE
 PS50968; BIOTINYL_LIPOYL
 PS00189; LIPOYL 
PRINTS