CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-004298
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Superoxide dismutase [Cu-Zn] B 
Protein Synonyms/Alias
 XSODB 
Gene Name
 sod1-b 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Xenopus laevis (African clawed frog) 
NCBI Taxa ID
 8355 
Lysine Modification
Position
Peptide
Type
References
96EGGVAQFKITDSLISacetylation[1]
Reference
 [1] A biotin switch-based proteomics approach identifies 14-3-3ΞΆ as a target of Sirt1 in the metabolic regulation of caspase-2.
 Andersen JL, Thompson JW, Lindblom KR, Johnson ES, Yang CS, Lilley LR, Freel CD, Moseley MA, Kornbluth S.
 Mol Cell. 2011 Sep 2;43(5):834-42. [PMID: 21884983
Functional Description
 Destroys radicals which are normally produced within the cells and which are toxic to biological systems. 
Sequence Annotation
 METAL 45 45 Copper; catalytic.
 METAL 47 47 Copper; catalytic.
 METAL 62 62 Copper; catalytic.
 METAL 62 62 Zinc; structural.
 METAL 70 70 Zinc; structural.
 METAL 79 79 Zinc; structural.
 METAL 82 82 Zinc; structural.
 METAL 118 118 Copper; catalytic.
 DISULFID 56 144  
Keyword
 3D-structure; Antioxidant; Copper; Cytoplasm; Direct protein sequencing; Disulfide bond; Metal-binding; Oxidoreductase; Zinc. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 151 AA 
Protein Sequence
MVKAVCVLAG SGDVKGVVHF EQQDEGAVSV EGKIEGLTDG LHGFHIHVFG DNTNGCMSAG 60
SHFNPENKNH GAPGDTDRHV GDLGNVTAEG GVAQFKITDS LISLKGPNSI IGRTAVVHEK 120
ADDLGKGGND ESLKTGNAGG RLACGVIGYS P 151 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0004784; F:superoxide dismutase activity; IEA:EC.
 GO:0006801; P:superoxide metabolic process; IEA:InterPro. 
Interpro
 IPR024134; SOD_Cu/Zn_/chaperones.
 IPR018152; SOD_Cu/Zn_BS.
 IPR001424; SOD_Cu_Zn_dom. 
Pfam
 PF00080; Sod_Cu 
SMART
  
PROSITE
 PS00087; SOD_CU_ZN_1
 PS00332; SOD_CU_ZN_2 
PRINTS
 PR00068; CUZNDISMTASE.