UniProt Accession

 B4DX29_HUMAN; B4DX29 

Genbank Protein ID

 AC090589; AK301785 

Genbank Nucleotide ID

 BAG63241.1 

Protein Name

 ADP-ribosylation factor GTPase-activating protein 2 

Protein Synonyms/Alias

 Uncharacterized protein; cDNA FLJ53674, highly similar to Homo sapiens zinc finger protein 289, ID1 regulated (ZNF289), mRNA 

Gene Name

 ARFGAP2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
102	PKASLELKSSIIGKK	ubiquitination	[1]
191	KLQNLEGKKREQAER	acetylation	[2]
229	QETPVSAKSSRSQLD	ubiquitination	[1]
250	TFASGPPKYKDNPFS	ubiquitination	[1]
252	ASGPPKYKDNPFSLG	ubiquitination	[1, 2]
322	RQKFAGAKAISSDMF	ubiquitination	[1, 3]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 414 AA 

Protein Sequence

Gene Ontology

 GO:0005794; C:Golgi apparatus; IDA:HPA.
 GO:0005730; C:nucleolus; IDA:HPA. 

Interpro

  

Pfam

  

SMART

  

PROSITE

  

PRINTS