CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029509
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein SEC13 homolog 
Protein Synonyms/Alias
  
Gene Name
 SEC13 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
24CSSDRSVKIFDVRNGubiquitination[1, 2, 3]
161IDHPSGQKPNYIKRFubiquitination[1, 2]
166GQKPNYIKRFASGGCubiquitination[2]
178GGCDNLIKLWKEEEDubiquitination[2]
242SSNTWSPKLLHKFNDubiquitination[1, 2, 3]
246WSPKLLHKFNDVVWHubiquitination[2, 3]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Repeat; WD repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 284 AA 
Protein Sequence
MIHDAQMDYY GTRLATCSSD RSVKIFDVRN GGQILIADLR GHEGPVWQVA WAHPMYGNIL 60
ASCSYDRKVI IWREENGTWE KSHEHAGHDS SVNSVCWAPH DYGLILACGS SDGAISLLTY 120
TGEGQWEVKK INNAHTIGCN AVSWAPAVVP GSLIDHPSGQ KPNYIKRFAS GGCDNLIKLW 180
KEEEDGQWKE EQKLEAHSDW VRDVAWAPSI GLPTSTIASC SQDGRVFIWT CDDASSNTWS 240
PKLLHKFNDV VWHVSWSITA NILAVSGGDN KEELQMQPQI DHLP 284 
Gene Ontology
  
Interpro
 IPR015943; WD40/YVTN_repeat-like_dom.
 IPR001680; WD40_repeat.
 IPR017986; WD40_repeat_dom. 
Pfam
 PF00400; WD40 
SMART
 SM00320; WD40 
PROSITE
 PS50082; WD_REPEATS_2
 PS50294; WD_REPEATS_REGION 
PRINTS