CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029993
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Plastin-3 
Protein Synonyms/Alias
  
Gene Name
 Pls3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
18KDELDELKEAFAKVDubiquitination[1]
59KVREIIQKLMVDGDRacetylation[2]
91VKSSDIAKTFRKAINacetylation[2]
266ETLEELMKLSPEELLubiquitination[1]
344FNETDDLKRAESMLQubiquitination[1]
355SMLQQADKLGCRQFVacetylation[2]
355SMLQQADKLGCRQFVubiquitination[1]
446LQLYERIKVPVDWSKubiquitination[1]
468KLGANMKKLENCNYAacetylation[2]
468KLGANMKKLENCNYAubiquitination[1]
546RTLSEAGKSTSIQSFubiquitination[1]
620PEDLVEVKPKMVMTVubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 
Functional Description
  
Sequence Annotation
  
Keyword
 Actin-binding; Calcium; Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 639 AA 
Protein Sequence
MDEMATTQIS KDELDELKEA FAKVDLNSNG FICDYELHEL FKEANMPLPG YKVREIIQKL 60
MVDGDRNKDG KISFNEFVYI FQEVKSSDIA KTFRKAINRK EGICALGGTS ELSSEGTQHS 120
YSEEEKYAFV NWINKALEND PDCRHVIPMN PNTDDLFKAV GDGIVLCKMI NLSVPDTIDE 180
RAINKKKLTP FIIQENLNLA LNSASAIGCH VVNIGAEDLR AGKPHLVLGL LWQIIKIGLF 240
ADIELSRNEA LAALLRDGET LEELMKLSPE ELLLRWANFH LENSGWQKIN NFSADIKLID 300
FSNSVKDSKA YFHLLNQIAP KGQKEGEPRI DINMSGFNET DDLKRAESML QQADKLGCRQ 360
FVTPADVVSG NPKLNLAFVA NLFNKYPALT KPENQDIDWT LLEGETREER TFRNWMNSLG 420
VNPHVNHLYA DLQDALVILQ LYERIKVPVD WSKVNKPPYP KLGANMKKLE NCNYAVELGK 480
NPAKFSLVGI GGQDLNDGNP TLTLAVVWQL MRRYTLNVLE DLGEGQKAND DIIVNWVNRT 540
LSEAGKSTSI QSFKDKTISS SLAVVDLIDA IQPGCINYDL VKSGNLTEDD KHNNAKYAVS 600
MARRIGARVY ALPEDLVEVK PKMVMTVFAC LMGRGMKRV 639 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0005509; F:calcium ion binding; IEA:InterPro. 
Interpro
 IPR001589; Actinin_actin-bd_CS.
 IPR001715; CH-domain.
 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom. 
Pfam
 PF00307; CH
 PF13499; EF_hand_5 
SMART
 SM00033; CH
 SM00054; EFh 
PROSITE
 PS00019; ACTININ_1
 PS00020; ACTININ_2
 PS50021; CH
 PS00018; EF_HAND_1
 PS50222; EF_HAND_2 
PRINTS