CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041610
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Interferon-inducible double stranded RNA-dependent protein kinase activator A 
Protein Synonyms/Alias
 Protein kinase, interferon inducible double stranded RNA dependent activator, isoform CRA_b 
Gene Name
 Prkra 
Gene Synonyms/Alias
 rCG_27414 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
25SGTFSLGKMITAKPGacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Kinase; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 313 AA 
Protein Sequence
MSHSRHRAEA PPLQREDSGT FSLGKMITAK PGKTPIQVLH EYGMKTKNIP VYECERSDVQ 60
VHVPTFTFRV TVGDITCTGE GTSKKLAKHR AAEAAINILK ANASICFAVP DPLMPDPSKQ 120
PKNQLNPIGS LQELAIHHGW RLPEYTLSQE GGPAHKREYT TICRLESFME TGKGASKKQA 180
KRNAAEKFLA KFSNISPENH ISLTNVVGHS LGCTWHSLRN SPGEKINLLK RSLLSLPNTD 240
YIQLLSEIAK EQGFSITYLD IEELSANGQY QCLAELSTSP ITVCHGSGIS CGNAQSDAAH 300
NALQYLKIIA ERK 313 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:Compara.
 GO:0003725; F:double-stranded RNA binding; IEA:InterPro.
 GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
 GO:0006917; P:induction of apoptosis; IEA:Compara.
 GO:0042474; P:middle ear morphogenesis; IEA:Compara.
 GO:0042473; P:outer ear morphogenesis; IEA:Compara.
 GO:0030422; P:production of siRNA involved in RNA interference; IEA:Compara.
 GO:0006468; P:protein phosphorylation; IEA:Compara.
 GO:0006950; P:response to stress; IEA:Compara.
 GO:0048705; P:skeletal system morphogenesis; IEA:Compara. 
Interpro
 IPR001159; Ds-RNA-bd.
 IPR014720; dsRNA-bd-like_dom. 
Pfam
 PF00035; dsrm 
SMART
 SM00358; DSRM 
PROSITE
 PS50137; DS_RBD 
PRINTS