CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-027836
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Cytochrome P450, CYP3A 
Protein Synonyms/Alias
 Cytochrome P450, family 3, subfamily a, polypeptide 44; MCG115423; Protein Cyp3a44 
Gene Name
 Cyp3a44 
Gene Synonyms/Alias
 cyp3a; mCG_115423 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
488QGILQPEKPIVLKVVacetylation[1]
493PEKPIVLKVVPRDAVacetylation[1]
Reference
 [1] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Heme; Iron; Metal-binding; Monooxygenase; Oxidoreductase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 504 AA 
Protein Sequence
MNLFSALSLD TLVLLAIILV LLYRYGTRTH GLFKKQGIPG PKPLPFLGTV LNYYTGIWKF 60
DMECYEKYGK TWGLFDGQTP LLVITDPETI KNVLVKDCLS VFTNRREFGP VGIMSKAISI 120
SKDEEWKRYR ALLSPTFTSG RLKEMFPVIE QYGDILVKYL RQEAEKGMPV AMKDVLGAYS 180
MDVITSTSFG VNVDSLNNPE DPFVEEAKKF LRVDFFDPLL FSVVLFPLLT PVYEMLNICM 240
FPNDSIEFFK KFVDRMQESR LDSNQKHRVD FLQLMMNSHN NSKDKDSHKA FSNMEITVQS 300
IIFISAGYET TSSTLSFTLY CLATHPDIQK KLQAEIDKAL PNKATPTCDT VMEMEYLDMV 360
LNETLRLYPI VTRLERVCKK DVELNGVYIP KGSMVMIPSY ALHHDPQHWP DPEEFQPERF 420
SKENKGSIDP YVYLPFGIGP RNCIGMRFAL MNMKLAVTKV LQNFSFQPCQ ETQIPLKLSR 480
QGILQPEKPI VLKVVPRDAV ITGA 504 
Gene Ontology
 GO:0009055; F:electron carrier activity; IEA:InterPro.
 GO:0020037; F:heme binding; IEA:InterPro.
 GO:0005506; F:iron ion binding; IEA:InterPro.
 GO:0016712; F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen; IEA:InterPro. 
Interpro
 IPR001128; Cyt_P450.
 IPR017972; Cyt_P450_CS.
 IPR008072; Cyt_P450_E_CYP3A.
 IPR002402; Cyt_P450_E_grp-II. 
Pfam
 PF00067; p450 
SMART
  
PROSITE
 PS00086; CYTOCHROME_P450 
PRINTS
 PR00464; EP450II.
 PR01689; EP450IICYP3A.
 PR00385; P450.