CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-021669
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Uncharacterized protein KIAA1551 
Protein Synonyms/Alias
  
Gene Name
 KIAA1551 
Gene Synonyms/Alias
 C12orf35 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
6**MNWNEKPKSATLPubiquitination[1, 2]
8MNWNEKPKSATLPPLubiquitination[1, 2]
204WTQQCISKGLTYPDYubiquitination[2]
216PDYRPPPKLYRYSPQubiquitination[2]
233LPDSTIQKQNFIPHTubiquitination[2]
245PHTSLQVKNSQLLNSubiquitination[1, 3]
275QYATQTDKRPPPPPYubiquitination[2]
299QSTQHITKHLSMEVPubiquitination[2]
341IGNFTNLKVNTNSKQubiquitination[2]
347LKVNTNSKQPFNSPIubiquitination[2]
371LAQTNEEKIMDSCNPubiquitination[2]
390VLDTSVAKEKLVRDIubiquitination[2]
392DTSVAKEKLVRDIKTubiquitination[2]
398EKLVRDIKTLVEIKQubiquitination[2]
404IKTLVEIKQKFSELAubiquitination[1, 2]
406TLVEIKQKFSELARKubiquitination[2]
418ARKIKINKDLLMAAGubiquitination[2]
442SEPAQNSKLSLKQTAubiquitination[1, 2]
446QNSKLSLKQTAKIQSubiquitination[2]
450LSLKQTAKIQSGPQIubiquitination[2]
528DVKVLTSKTSAVEMTubiquitination[2]
566CETISVPKSMSTEEYubiquitination[2]
574SMSTEEYKSKIQNENubiquitination[2]
576STEEYKSKIQNENMLubiquitination[2]
600KTQKTVLKDANQTIQubiquitination[2]
658SGQESSTKGMPAKSDubiquitination[1, 2]
663STKGMPAKSDSSCSMubiquitination[2]
707TTAVGISKPANIHVKubiquitination[2, 4]
714KPANIHVKSPCSVVGubiquitination[2]
772PLVLSEVKTLSVKGIubiquitination[2]
777EVKTLSVKGITPAVLubiquitination[1, 2, 4]
793ETVYPVIKEGSVCSLubiquitination[2, 4]
809NQLAENAKATAALKVubiquitination[2, 4]
815AKATAALKVDVSGPVubiquitination[2, 4]
830ASTATSTKIFPLTQKubiquitination[2, 4]
839FPLTQKEKQNESTNGubiquitination[2]
958DFGFQKDKPVQCTDVubiquitination[2]
968QCTDVSHKICDQSKSubiquitination[4]
995TNRVILEKSSLEHATubiquitination[4]
1202NSSSEEEKQKEQCSPubiquitination[2]
1204SSEEEKQKEQCSPLDubiquitination[2]
1282VAGQFSSKCDKLNPLubiquitination[4]
1367EKIKLKLKSVSFKQKubiquitination[2]
1429EKMVSNTKSVDTKASmethylation[5]
1537YNILRNVKEKVGGKQacetylation[4]
1629PVKGNTEKSNMLEFKubiquitination[2]
Reference
 [1] Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition.
 Udeshi ND, Mani DR, Eisenhaure T, Mertins P, Jaffe JD, Clauser KR, Hacohen N, Carr SA.
 Mol Cell Proteomics. 2012 May;11(5):148-59. [PMID: 22505724]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [5] Large-scale global identification of protein lysine methylation in vivo.
 Cao XJ, Arnaudo AM, Garcia BA.
 Epigenetics. 2013 May 1;8(5):477-85. [PMID: 23644510
Functional Description
  
Sequence Annotation
 MOD_RES 1358 1358 Phosphoserine.  
Keyword
 Complete proteome; Phosphoprotein; Polymorphism; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1747 AA 
Protein Sequence
MNWNEKPKSA TLPPLYPKSQ PPFLHQSLIN QITTTSQSSF SYPGSNQEAC MYPGNSNPIS 60
QPLLNIQNYP QQISVSDMHN GTVVASHTSV ERITYANVNG PKQLTHNLQM SSGVTQNVWL 120
NSPMRNPVHS HIGATVSHQT DFGANVPNMP ALQSQLITSD TYSMQMQMIP SNSTRLPVAY 180
QGNQGLNQSF SEQQVDWTQQ CISKGLTYPD YRPPPKLYRY SPQSFLPDST IQKQNFIPHT 240
SLQVKNSQLL NSVLTLPSRQ TSAVPSQQYA TQTDKRPPPP PYNCRYGSQP LQSTQHITKH 300
LSMEVPQSRE MLSSEIRTSF QQQWQNPNEN VSTIGNFTNL KVNTNSKQPF NSPIRSSVDG 360
VQTLAQTNEE KIMDSCNPTS NQVLDTSVAK EKLVRDIKTL VEIKQKFSEL ARKIKINKDL 420
LMAAGCIKMT NTSYSEPAQN SKLSLKQTAK IQSGPQITPV MPENAERQTP TVVESAETNK 480
TQCMLNSDIQ EVNCRRFNQV DSVLPNPVYS EKRPMPDSSH DVKVLTSKTS AVEMTQAVLN 540
TQLSSENVTK VEQNSPAVCE TISVPKSMST EEYKSKIQNE NMLLLALLSQ ARKTQKTVLK 600
DANQTIQDSK PDSCEMNPNT QMTGNQLNLK NMETPSTSNV SGRVLDNSFC SGQESSTKGM 660
PAKSDSSCSM EVLATCLSLW KKQPSDTAKE KECDKLRTNT TAVGISKPAN IHVKSPCSVV 720
GNSNSQNKIS NPSQQTALSM VMHNYESSGI NITKGTELQI AVVSPLVLSE VKTLSVKGIT 780
PAVLPETVYP VIKEGSVCSL QNQLAENAKA TAALKVDVSG PVASTATSTK IFPLTQKEKQ 840
NESTNGNSEV TPNVNQGKHN KLESAIHSPM NDQQISQESR NSTVVSSDTL QIDNICSLVE 900
GDTSYNSQIA KIFSSLPLKM VEPQKPSLPN QQGIGSREPE KQLDNTTENK DFGFQKDKPV 960
QCTDVSHKIC DQSKSEPPLE SSFNNLETNR VILEKSSLEH ATEKSTANDT CSSAAIQEDI 1020
YPQEIDASSN YTPQDPARNE IHSDKAPVLY LHDQLSELLK EFPYGIEAVN TREGSVGQQT 1080
TYQTSEDQTA DKTSSDSKDP ADQIQITILS SEQMKEIFPE QDDQPYVVDK LAEPQKEEPI 1140
TEVVSQCDLQ APAAGQSRDS VILDSEKDDI HCCALGWLSM VYEGVPQCQC NSIKNSSSEE 1200
EKQKEQCSPL DTNSCKQGER TSDRDVTVVQ FKSLVNNPKT PPDGKSHFPE LQDDSRKDTP 1260
KTKHKSLPRT EQELVAGQFS SKCDKLNPLQ NHKRKKLRFH EVTFHSSNKM TASYEQASQE 1320
TRQKKHVTQN SRPLKTKTAF LPNKDVYKKH SSLGQSLSPE KIKLKLKSVS FKQKRKLDQG 1380
NVLDMEVKKK KHDKQEQKGS VGATFKLGDS LSNPNERAIV KEKMVSNTKS VDTKASSSKF 1440
SRILTPKEYL QRQKHKEALS NKASKKICVK NVPCDSEHMR PSKLAVQVES CGKSNEKHSS 1500
GVQTSKESLN GLTSHGKNLK IHHSQESKTY NILRNVKEKV GGKQPDKIWI DKTKLDKLTN 1560
ISNEAQFSQM PPQVKDQKKL YLNRVGFKCT ERESISLTKL ESSPRKLHKD KRQENKHKTF 1620
LPVKGNTEKS NMLEFKLCPD ILLKNTNSVE ERKDVKPHPR KEQAPLQVSG IKSTKEDWLK 1680
FVATKKRTQK DSQERDNVNS RLSKRSFSAD GFEMLQNPVK DSKEMFQTYK QMYLEKRSRS 1740
LGSSPVK 1747 
Gene Ontology
  
Interpro
  
Pfam
  
SMART
  
PROSITE
  
PRINTS