| Tag | Content |
|---|
| CPLM ID | CPLM-021691 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Magnesium transporter MRS2 homolog, mitochondrial |
Protein Synonyms/Alias | MRS2-like protein |
Gene Name | MRS2 |
Gene Synonyms/Alias | HPT; MRS2L |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 90 | APVFTVTKFDKQGNV | ubiquitination | [1] |
|
Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | Magnesium transporter that may mediate the influx of magnesium into the mitochondrial matrix. |
Sequence Annotation | |
Keyword | Alternative splicing; Complete proteome; Ion transport; Magnesium; Membrane; Mitochondrion; Mitochondrion inner membrane; Polymorphism; Reference proteome; Transit peptide; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 443 AA |
Protein Sequence | MECLRSLPCL LPRAMRLPRR TLCALALDVT SVGPPVAACG RRANLIGRSR AAQLCGPDRL 60
RVAGEVHRFR TSDVSQATLA SVAPVFTVTK FDKQGNVTSF ERKKTELYQE LGLQARDLRF 120
QHVMSITVRN NRIIMRMEYL KAVITPECLL ILDYRNLNLE QWLFRELPSQ LSGEGQLVTY 180
PLPFEFRAIE ALLQYWINTL QGKLSILQPL ILETLDALVD PKHSSVDRSK LHILLQNGKS 240
LSELETDIKI FKESILEILD EEELLEELCV SKWSDPQVFE KSSAGIDHAE EMELLLENYY 300
RLADDLSNAA RELRVLIDDS QSIIFINLDS HRNVMMRLNL QLTMGTFSLS LFGLMGVAFG 360
MNLESSLEED HRIFWLITGI MFMGSGLIWR RLLSFLGRQL EAPLPPMV 408 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell. GO:0015095; F:magnesium ion transmembrane transporter activity; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |