CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038916
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Peptidyl arginine deiminase, type II, isoform CRA_a 
Protein Synonyms/Alias
 Protein-arginine deiminase type-2 
Gene Name
 Padi2 
Gene Synonyms/Alias
 rCG_31371 
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
524GLGGMSSKRITINKIacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 665 AA 
Protein Sequence
MLRERTVRLQ YGSRVEAVYV LGTQLWTDVY SAAPAGAKTF SLKHSEGVKV EVVGDGEAEE 60
VVTNGKQRWA LSPSTTLRLS MAQASTEASS DKVTVNYYEE DGSAPIDQAG LFLTAIEISL 120
DVDADRDGEV EKNNPKKASW TWGPEGQGAI LLVNCDRDTP WLPKEDCSDE KVYSKQDLQD 180
MSQMILRTKG PDRLPAGYEI VLYISMSDSD KVGVFYVENP FFGQRYIHIL GRQKLYHVVK 240
YTGGSAELLF FVEGLRFPDE SFSGLVSIHV SLLEYMAEDI PLTPIFTDTV TFRIAPWIMT 300
PNILPPVSVF VCCMKDNYLF LKEVKNLVEK TNCELKVCFQ YMNRGDRWIQ DEIEFGYIEA 360
PHKGFPVVLD SPRDGNLKDF PIKQLLGPDF GYVTREPLFE TVTSLDSFGN LEVSPPVTVN 420
GKAYPLGRIL IGSSFPLSGG RRMTKVVRDF LQAQQVQAPV ELYSDWLTVG HVDEFMTFVP 480
IPGKKEFRLL MASTSACYQL FREKQKEGHG EAIMFKGLGG MSSKRITINK ILSNESLTQE 540
NQYFQRCLDW NRDILKKELA LTEKDIIDLP ALFKMDEDRQ ARAFFPNMVN MIVLDKDLGI 600
PKPFGPQVEE ECCLETHVRG LLEPLGLACT FIDDISAYHK FLGEVHCGTN VRRKPFTFKW 660
WHMVP 665 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0004668; F:protein-arginine deiminase activity; IEA:InterPro.
 GO:0018101; P:peptidyl-citrulline biosynthetic process from peptidyl-arginine; IEA:InterPro. 
Interpro
 IPR008972; Cupredoxin.
 IPR004303; PAD.
 IPR013530; PAD_C.
 IPR013732; PAD_N.
 IPR013733; Prot_Arg_deaminase_cen_dom.
 IPR016296; Protein-arginine_deiminase_sub. 
Pfam
 PF03068; PAD
 PF08527; PAD_M
 PF08526; PAD_N 
SMART
  
PROSITE
  
PRINTS