| Tag | Content |
|---|
| CPLM ID | CPLM-003530 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Nitrogen regulation protein NR(I) |
Protein Synonyms/Alias | |
Gene Name | glnG |
Gene Synonyms/Alias | glnT; ntrC; b3868; JW3839 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 67 | MDGLALLKQIKQRHP | acetylation | [1] | | 202 | LNMAAIPKDLIESEL | acetylation | [1] | | 214 | SELFGHEKGAFTGAN | acetylation | [1] | | 271 | VGGYAPVKVDVRIIA | acetylation | [1] | | 292 | EQRVQEGKFREDLFH | acetylation | [1] |
|
Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Member of the two-component regulatory system NtrB/NtrC involved in the activation of nitrogen assimilatory genes such as GlnA. NtrC is phosphorylated by NtrB and interacts with sigma-54. |
Sequence Annotation | DOMAIN 1 119 Response regulatory.
DOMAIN 140 369 Sigma-54 factor interaction.
NP_BIND 168 175 ATP (Potential).
NP_BIND 231 240 ATP (Potential).
DNA_BIND 445 464 H-T-H motif (By similarity).
MOD_RES 54 54 4-aspartylphosphate (By similarity). |
Keyword | Activator; ATP-binding; Complete proteome; DNA-binding; Nitrogen fixation; Nucleotide-binding; Phosphoprotein; Reference proteome; Repressor; Transcription; Transcription regulation; Two-component regulatory system. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 469 AA |
Protein Sequence | MQRGIVWVVD DDSSIRWVLE RALAGAGLTC TTFENGAEVL EALASKTPDV LLSDIRMPGM 60
DGLALLKQIK QRHPMLPVII MTAHSDLDAA VSAYQQGAFD YLPKPFDIDE AVALVERAIS 120
HYQEQQQPRN VQLNGPTTDI IGEAPAMQDV FRIIGRLSRS SISVLINGES GTGKELVAHA 180
LHRHSPRAKA PFIALNMAAI PKDLIESELF GHEKGAFTGA NTIRQGRFEQ ADGGTLFLDE 240
IGDMPLDVQT RLLRVLADGQ FYRVGGYAPV KVDVRIIAAT HQNLEQRVQE GKFREDLFHR 300
LNVIRVHLPP LRERREDIPR LARHFLQVAA RELGVEAKLL HPETEAALTR LAWPGNVRQL 360
ENTCRWLTVM AAGQEVLIQD LPGELFESTV AESTSQMQPD SWATLLAQWA DRALRSGHQN 420
LLSEAQPELE RTLLTTALRH TQGHKQEAAR LLGWGRNTLT RKLKELGME 469 |
Gene Ontology | GO:0005524; F:ATP binding; IEA:UniProtKB-KW. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. GO:0000156; F:phosphorelay response regulator activity; IEA:InterPro. GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. GO:0035556; P:intracellular signal transduction; IEA:GOC. GO:0009399; P:nitrogen fixation; IEA:UniProtKB-KW. GO:0006808; P:regulation of nitrogen utilization; IEA:InterPro. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |