CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025262
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Arginine vasopressin receptor 1A 
Protein Synonyms/Alias
  
Gene Name
 Avpr1a 
Gene Synonyms/Alias
 mCG_10108 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
285TPCVSSVKSISRAKIubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
  
Keyword
 G-protein coupled receptor; Membrane; Receptor; Transducer; Transmembrane. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 423 AA 
Protein Sequence
MSFPRGSHDL PAGNSSPWWP LTTEGANSSR EAAGLGEGGS PPGDVRNEEL AKLEVTVLAV 60
IFVVAVLGNS SVLLALHRTP RKTSRMHLFI RHLSLADLAV AFFQVLPQLC WDITYRFRGP 120
DWLCRVVKHL QVFAMFASSY MLVVMTADRY IAVCHPLKTL QQPARRSRLM IAASWGLSFV 180
LSIPQYFIFS VIEFEVNNGT KAQDCWATFI PPWGTRAYVT WMTSGVFVVP VIILGTCYGF 240
ICYHIWRNVR GKTASRQSKG GKGSGEAAGP FHKGLLVTPC VSSVKSISRA KIRTVKMTFV 300
IVSAYILCWT PFFIVQMWSV WDTNFVWTDS ENPSTTITAL LASLNSCCNP WIYMFFSGHL 360
LQDCVQSFPC CQSIAQKFAK DDSDSMSRRQ TSYSNNRSPT NSTGTWKDSP KSSKSIRFIP 420
VST 423 
Gene Ontology
 GO:0031410; C:cytoplasmic vesicle; IEA:Compara.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0017046; F:peptide hormone binding; IEA:Compara.
 GO:0005000; F:vasopressin receptor activity; IEA:InterPro.
 GO:0019722; P:calcium-mediated signaling; IEA:Compara.
 GO:0042631; P:cellular response to water deprivation; IEA:Compara.
 GO:0007204; P:elevation of cytosolic calcium ion concentration; IEA:Compara.
 GO:0007625; P:grooming behavior; IEA:Compara.
 GO:0002125; P:maternal aggressive behavior; IEA:Compara.
 GO:0042711; P:maternal behavior; IEA:Compara.
 GO:0014902; P:myotube differentiation; IEA:Compara.
 GO:0007621; P:negative regulation of female receptivity; IEA:Compara.
 GO:0051970; P:negative regulation of transmission of nerve impulse; IEA:Compara.
 GO:0043084; P:penile erection; IEA:Compara.
 GO:0030307; P:positive regulation of cell growth; IEA:Compara.
 GO:0008284; P:positive regulation of cell proliferation; IEA:Compara.
 GO:0032849; P:positive regulation of cellular pH reduction; IEA:Compara.
 GO:0014049; P:positive regulation of glutamate secretion; IEA:Compara.
 GO:0010460; P:positive regulation of heart rate; IEA:Compara.
 GO:0031394; P:positive regulation of prostaglandin biosynthetic process; IEA:Compara.
 GO:0035815; P:positive regulation of renal sodium excretion; IEA:Compara.
 GO:0003084; P:positive regulation of systemic arterial blood pressure; IEA:Compara.
 GO:0045907; P:positive regulation of vasoconstriction; IEA:Compara.
 GO:0001992; P:regulation of systemic arterial blood pressure by vasopressin; IGI:MGI.
 GO:0051412; P:response to corticosterone stimulus; IEA:Compara.
 GO:0035176; P:social behavior; IEA:Compara.
 GO:0042713; P:sperm ejaculation; IEA:Compara.
 GO:0021537; P:telencephalon development; IEA:Compara. 
Interpro
 IPR015076; DUF1856.
 IPR000276; GPCR_Rhodpsn.
 IPR017452; GPCR_Rhodpsn_7TM.
 IPR001817; Vasoprsn_rcpt.
 IPR001224; Vprs_V1A_rcpt. 
Pfam
 PF00001; 7tm_1
 PF08983; DUF1856 
SMART
  
PROSITE
 PS00237; G_PROTEIN_RECEP_F1_1
 PS50262; G_PROTEIN_RECEP_F1_2 
PRINTS
 PR00237; GPCRRHODOPSN.
 PR00896; VASOPRESSINR.
 PR00752; VASOPRSNV1AR.