UniProt Accession

 RHOD_HUMAN; O00212 

Genbank Protein ID

 D85815; AF498973; AP000729; BC001338 

Genbank Nucleotide ID

 BAA19652.1; AAM21120.1; AAH01338.1 

Protein Name

 Rho-related GTP-binding protein RhoD 

Protein Synonyms/Alias

 Rho-related protein HP1; RhoHP1 

Gene Name

 RHOD 

Gene Synonyms/Alias

 ARHD 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
63	VNLQVKGKPVHLHIW	ubiquitination	[1]
120	PEVNHFCKKVPIIVV	ubiquitination	[2]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 

Functional Description

 Involved in endosome dynamics. May coordinate membrane transport with the function of the cytoskeleton. Participates in reorganization of actin cytoskeleton (By similarity). 

Sequence Annotation

 NP_BIND 24 31 GTP (By similarity).
 NP_BIND 71 75 GTP (By similarity).
 NP_BIND 129 132 GTP (By similarity).
 MOTIF 46 54 Effector region (Potential).
 MOD_RES 207 207 Cysteine methyl ester (By similarity).
 LIPID 207 207 S-geranylgeranyl cysteine (By  

Keyword

 3D-structure; Cell membrane; Complete proteome; GTP-binding; Lipoprotein; Membrane; Methylation; Nucleotide-binding; Polymorphism; Prenylation; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 210 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; TAS:Reactome.
 GO:0005886; C:plasma membrane; TAS:Reactome.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0003924; F:GTPase activity; TAS:ProtInc.
 GO:0051056; P:regulation of small GTPase mediated signal transduction; TAS:Reactome.
 GO:0007266; P:Rho protein signal transduction; TAS:ProtInc. 

Interpro

 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR001806; Small_GTPase.
 IPR003578; Small_GTPase_Rho. 

Pfam

 PF00071; Ras 

SMART

 SM00174; RHO 

PROSITE

 PS51420; RHO 

PRINTS

 PR00449; RASTRNSFRMNG.