| Tag | Content |
|---|
| CPLM ID | CPLM-015774 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Mitochondrial enolase superfamily member 1 |
Protein Synonyms/Alias | Antisense RNA to thymidylate synthase; rTS |
Gene Name | ENOSF1 |
Gene Synonyms/Alias | RTS; TYMSAS |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 222 | GWTRFKVKVGADLQD | ubiquitination | [1] | | 266 | EAVEWMSKLAKFKPL | ubiquitination | [1] | | 269 | EWMSKLAKFKPLWIE | ubiquitination | [1] | | 436 | PDGEVWKKLLPAQEN | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May regulate thymidylate synthase activity. |
Sequence Annotation | ACT_SITE 222 222 By similarity.
ACT_SITE 355 355 By similarity.
METAL 250 250 Magnesium (By similarity).
METAL 276 276 Magnesium (By similarity).
METAL 305 305 Magnesium (By similarity).
MOD_RES 148 148 Phosphoserine. |
Keyword | 3D-structure; Alternative splicing; Complete proteome; Isomerase; Magnesium; Metal-binding; Mitochondrion; Phosphoprotein; Polymorphism; Reference proteome; Ubl conjugation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 443 AA |
Protein Sequence | MVRGRISRLS VRDVRFPTSL GGHGADAMHT DPDYSAAYVV IETDAEDGIK GCGITFTLGK 60
GTEVVVCAVN ALAHHVLNKD LKDIVGDFRG FYRQLTSDGQ LRWIGPEKGV VHLATAAVLN 120
AVWDLWAKQE GKPVWKLLVD MDPRMLVSCI DFRYITDVLT EEDALEILQK GQIGKKEREK 180
QMLAQGYPAY TTSCAWLGYS DDTLKQLCAQ ALKDGWTRFK VKVGADLQDD MRRCQIIRDM 240
IGPEKTLMMD ANQRWDVPEA VEWMSKLAKF KPLWIEEPTS PDDILGHATI SKALVPLGIG 300
IATGEQCHNR VIFKQLLQAK ALQFLQIDSC RLGSVNENLS VLLMAKKFEI PVCPHAGGVG 360
LCELVQHLII FDYISVSASL ENRVCEYVDH LHEHFKYPVM IQRASYMPPK DPGYSTEMKE 420
ESVKKHQYPD GEVWKKLLPA QEN 443 |
Gene Ontology | GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell. GO:0016853; F:isomerase activity; IEA:UniProtKB-KW. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0009063; P:cellular amino acid catabolic process; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |