| Tag | Content |
|---|
| CPLM ID | CPLM-013123 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | WASH complex subunit 7 |
Protein Synonyms/Alias | |
Gene Name | Kiaa1033 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 898 | KFNRGIRKLGITPEG | ubiquitination | [1] | | 1089 | KEIRAVAKQQNVQST | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Component of the WASH complex, a complex present at the surface of endosomes that recruits and activates the Arp2/3 complex to induce actin polymerization. The WASH complex plays a key role in the fission of tubules that serve as transport intermediates during endosome sorting. |
Sequence Annotation | MOD_RES 2 2 N-acetylalanine (By similarity).
MOD_RES 7 7 Phosphoserine (By similarity). |
Keyword | Acetylation; Coiled coil; Complete proteome; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1173 AA |
Protein Sequence | MAVDTLSPDW DFDRVDDGSQ KIHAEVQLKN YGRFLEEYTS QLRRIEDALD DLIGDVWDFN 60
LDPIALKLLP YEQSSLLELI KTENKVLNKV ITVYAALCCE IKKLKYEAET KFYNGLLFYG 120
EGATDSSMVE GDCQIQMGRF VSFLQELSCF VTRCYEVVMN VIHQLAALYI SNKIGPKIIE 180
TTGVHFQTMY EHLGELLTVL LTLDEIVDNH VTLKDHWTMY KRLLKSVHHN PSKFGIQEEK 240
LKPFEKFLLK LEGQLLDGMI FQACIEQQFD SLNGGISVSK NSTFAEEFAH SIRSIFANVE 300
AKLGEPSEID QRDKYVGICG LFVLHFQIFR TVDKKFYKSL LDICKKVPAI TLTANIIWFP 360
DNFLIHKMPA AAKLLDRKSL QAIKIHRDTF LQQKAQSLNK DVQSYYVFVS SWMMKMESML 420
SKEQRMDTFA EDLTNRCNVF IQGFLYAYSI STIIKTTMNL YMSMQKPMTK TSVKALCRLI 480
ELLKAIEHMF YRRSMVVADS VSHITQHLQH QALSSISVAK KRVISDKKYS EQRLDVLSAL 540
VLAENTLNGP STKQRRLIVS LALSVGTQMK TFKDEELFPL QVVMKKLDLI SELRERVQAQ 600
CDCCFLYWHR AVFPIYLDDV YENAVDAARL HYMFSALRDC VPAMMHSRHL ESHELLLDCY 660
DKEIMDILNE HLLDKLCKEI EKDLRLSVHT HLKLDDRNPF KVGRKDLALF FSLNPIRFFN 720
RFIDIRAYVT HYLDKTFYNL TTVALHDWAT YSEMRNLATQ RYGLVMTEAH LPSQTLEQGL 780
DVLEIMRNIH IFVSRYLYNL NNQIFIERTS NNKHLNTINI RHIANSIRTH GTGIMNTTVN 840
FTYQFLKKKF YIFSQFMYDE HIKSRLIKDI RFFREIKDQN DHKYPFDRAE KFNRGIRKLG 900
ITPEGQSYLD QFRQLISQIG NAMGYIRMIR SGGLHCSSNA IRFVPDLEDI VSFEELVKEE 960
GLAEETLRAA RHLDSVLSDH TRNSAEGTEY FKMLVDVFAP EFRRPKNIHL RNFYIIVPPL 1020
TLNFVEHSIS CKEKLNKKNK LGAAFTDDGF AMGVAYTLKL LDQYQEFDSL HWFQSVREKY 1080
IKEIRAVAKQ QNVQSTSQDE KLLQTMNLTQ KRLEVYLQEF ELLYFSLSSA RIFFRADKTA 1140
AEENQEKKEK EEETKTSNGD GPESTVSADP VVK 1173 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |