| Tag | Content |
|---|
| CPLM ID | CPLM-000218 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | mRNA-capping enzyme subunit beta |
Protein Synonyms/Alias | Polynucleotide 5'-triphosphatase; mRNA 5'-triphosphatase; TPase |
Gene Name | CET1 |
Gene Synonyms/Alias | YPL228W; P1433 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 32 | NEKVKLQKLSEAANG | acetylation | [1] | | 444 | PDNDPPEKYKSQSPI | acetylation | [1] |
|
Reference | [1] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C. Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [ PMID: 22865919] |
Functional Description | First step of mRNA capping. Converts the 5'-triphosphate end of a nascent mRNA chain into a diphosphate end. |
Sequence Annotation | ACT_SITE 223 223 N6-GMP-lysine intermediate.
MOD_RES 15 15 Phosphoserine.
MOD_RES 124 124 Phosphoserine. |
Keyword | 3D-structure; Complete proteome; Hydrolase; mRNA capping; mRNA processing; Nucleus; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 549 AA |
Protein Sequence | MSYTDNPPQT KRALSLDDLV NHDENEKVKL QKLSEAANGS RPFAENLESD INQTETGQAA 60
PIDNYKESTG HGSHSQKPKS RKSSNDDEET DTDDEMGASG EINFDSEMDF DYDKQHRNLL 120
SNGSPPMNDG SDANAKLEKP SDDSIHQNSK SDEEQRIPKQ GNEGNIASNY ITQVPLQKQK 180
QTEKKIAGNA VGSVVKKEEE ANAAVDNIFE EKATLQSKKN NIKRDLEVLN EISASSKPSK 240
YRNVPIWAQK WKPTIKALQS INVKDLKIDP SFLNIIPDDD LTKSVQDWVY ATIYSIAPEL 300
RSFIELEMKF GVIIDAKGPD RVNPPVSSQC VFTELDAHLT PNIDASLFKE LSKYIRGISE 360
VTENTGKFSI IESQTRDSVY RVGLSTQRPR FLRMSTDIKT GRVGQFIEKR HVAQLLLYSP 420
KDSYDVKISL NLELPVPDND PPEKYKSQSP ISERTKDRVS YIHNDSCTRI DITKVENHNQ 480
NSKSRQSETT HEVELEINTP ALLNAFDNIT NDSKEYASLI RTFLNNGTII RRKLSSLSYE 540
IFEGSKKVM 549 |
Gene Ontology | GO:0031533; C:mRNA cap methyltransferase complex; IPI:SGD. GO:0004651; F:polynucleotide 5'-phosphatase activity; IDA:SGD. GO:0016740; F:transferase activity; IEA:InterPro. GO:0006370; P:7-methylguanosine mRNA capping; TAS:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |