CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037243
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Kinesin superfamily protein 16B 
Protein Synonyms/Alias
  
Gene Name
 Kif16b 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
39KTTITNLKIPEGGTGubiquitination[1]
235TIKFTQAKFDAEMPCubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Microtubule; Motor protein; Nucleotide-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1323 AA 
Protein Sequence
MASVKVAVRV RPMNRREKDL EAKFIIQMEK SKTTITNLKI PEGGTGDSGR ERTKTFTYDF 60
SFYSADTKSP DYVSQEMVFK TLGTDVVKSA FEGYNACVFA YGQTGSGKSY TMMGNSGDSG 120
LIPRICEALF SRINETTRWD EASFRTEVSY LEIYNERVRD LLRRKSSKTF NLRVREHPKE 180
GPYVEDLSKH LVQNYSDVEE LMDAGNINRT TAATGMNDVS SRSHAIFTIK FTQAKFDAEM 240
PCETVSKIHL VDLAGSERAD ATGATGVRLK EGGNINKSLV TLGNVISALA DLSQDAANPL 300
VKKKQVFVPY RDSVLTWLLK DSLGGNSKTI MIATISPADV NYGETLSTLR YANRAKNIIN 360
KPTINEDANV KLIRELRAEI ARLKTLLAQG NQIALLDSPT ALSMEEKLHQ NEARVQELTK 420
EWTNKWNETQ NILKEQTLAL RKEGIGVVLD SELPHLIGID DDLLSTGIIL YHLKEGQTYV 480
GREDASTEQD IVLHGLDLES EHCVFENAGG TVTLIPLRGS QCSVNGVQIV DATQLNQGAV 540
ILLGRTNMFR FNHPKEAAKL REKRKSGLLS SFSLSMTDLS KSCENLSAVM LYNPGLFPIK 600
GPICLRLEFE RQQREELEKL ESKRKLIEEM EEKQKSDKAE LERMQQEVET RRKETEIVQR 660
QIRKQEESLK RRSFHIENKL KDLLAEKERF EEERLREQQG LEQQRRQEEE SLFRIREELR 720
KLQELNSHEQ AEKVQIFQEL DRLHQEQNAQ SAKLRLEKRR LEEEEKEQVQ RVAHLEEQLR 780
KRQDTAPLLC PGEAQRAQEE KRELESIREA LLQAKEMRAG GDHTCRDELE RAQQYFLEFK 840
RRQLVKLASL EKDLVQQKDL LSKEVQEEKV ALEHVKCDAG GDPSFLATDD GNILGGPPDL 900
DKIKTAETRL QSREHQLQDL LQNHLPALLE EKQRVLDALD SGVLGLDTTL CQVEKEVGEK 960
EEQIAQYQAN ASQLQQLRAT FEFTANVARQ EEKVRRKEKE ILESQEKQQR EALEQAVAKL 1020
EQRRSALQRC STLDLEIQEQ RQKLGSLHTS EWSGWQASLE TDGEALEMDP ARLEHEIHQL 1080
KQKICEVDGV QRPHHGILEG QAVLSSLPPS GGNSHLAPLM DARISAYIEE EVQRRLHDLH 1140
RAIGDANHTP ADVMKSNEEL HNGTTQRKLK YERMYSRSLG TNRDDLKDPI KISIPRYVLC 1200
GQGKDEHFEF EVKISVLDET WTVFRRYSRF REMHKTLKLK YAELAALEFP PKKLFGNKDE 1260
RVVAERRTHL EKYLREFFSV MLQSETSPLH INKVGLTLSK HTICEFSPFF KKGVFDYSSH 1320
GTG 1323 
Gene Ontology
 GO:0005769; C:early endosome; IEA:Compara.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0005875; C:microtubule associated complex; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0005547; F:phosphatidylinositol-3,4,5-trisphosphate binding; IEA:Compara.
 GO:0043325; F:phosphatidylinositol-3,4-bisphosphate binding; IEA:Compara.
 GO:0080025; F:phosphatidylinositol-3,5-bisphosphate binding; IEA:Compara.
 GO:0032266; F:phosphatidylinositol-3-phosphate binding; IEA:Compara.
 GO:0008574; F:plus-end-directed microtubule motor activity; IEA:Compara.
 GO:0045022; P:early endosome to late endosome transport; IEA:Compara.
 GO:0007173; P:epidermal growth factor receptor signaling pathway; IEA:Compara.
 GO:0007018; P:microtubule-based movement; IEA:InterPro.
 GO:0032801; P:receptor catabolic process; IEA:Compara.
 GO:0001919; P:regulation of receptor recycling; IEA:Compara. 
Interpro
 IPR000253; FHA_dom.
 IPR019821; Kinesin_motor_CS.
 IPR001752; Kinesin_motor_dom.
 IPR027417; P-loop_NTPase.
 IPR001683; Phox.
 IPR008984; SMAD_FHA_domain. 
Pfam
 PF00498; FHA
 PF00225; Kinesin
 PF00787; PX 
SMART
 SM00240; FHA
 SM00129; KISc
 SM00312; PX 
PROSITE
 PS00411; KINESIN_MOTOR_DOMAIN1
 PS50067; KINESIN_MOTOR_DOMAIN2
 PS50195; PX 
PRINTS
 PR00380; KINESINHEAVY.