UniProt Accession

 DESA2_MYCTU; O53442; L0T8L4; Q7D8V3 

Genbank Protein ID

 AE000516; AL123456 

Genbank Nucleotide ID

 AAK45384.1; CCP43847.1 

Protein Name

 Putative acyl-[acyl-carrier-protein] desaturase desA2 

Protein Synonyms/Alias

 DES; Putative acyl-ACP desaturase desA2 

Gene Name

 desA2 

Gene Synonyms/Alias

 Rv1094; MT1126 

Created Date

 July 27, 2013 

Organism

 Mycobacterium tuberculosis 

NCBI Taxa ID

 1773 

Lysine Modification

Position	Peptide	Type	References
145	MKGYRAEKYTQVETL	pupylation	[1]

Reference

 [1] Prokaryotic ubiquitin-like protein (Pup) proteome of Mycobacterium tuberculosis [corrected] .
 Festa RA, McAllister F, Pearce MJ, Mintseris J, Burns KE, Gygi SP, Darwin KH.
 PLoS One. 2010 Jan 6;5(1):e8589. [PMID: 20066036] 

Functional Description

 Could be involved in mycobacterial fatty acid biosynthesis. 

Sequence Annotation

 METAL 107 107 Iron.
 METAL 159 159 Iron.
 METAL 189 189 Iron.
 METAL 192 192 Iron.
 CROSSLNK 145 145 Isoglutamyl lysine isopeptide (Lys-Gln)  

Keyword

 3D-structure; Complete proteome; Fatty acid biosynthesis; Fatty acid metabolism; Iron; Isopeptide bond; Lipid biosynthesis; Lipid metabolism; Metal-binding; Oxidoreductase; Reference proteome; Ubl conjugation. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 275 AA 

Protein Sequence

Gene Ontology

 GO:0005618; C:cell wall; IDA:MTBBASE.
 GO:0005829; C:cytosol; IDA:MTBBASE.
 GO:0005886; C:plasma membrane; IDA:MTBBASE.
 GO:0045300; F:acyl-[acyl-carrier-protein] desaturase activity; IEA:InterPro.
 GO:0046872; F:metal ion binding; IDA:MTBBASE.
 GO:0046914; F:transition metal ion binding; IEA:InterPro.
 GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-KW.
 GO:0040007; P:growth; IMP:MTBBASE. 

Interpro

 IPR005067; Fatty_acid_desaturase-2.
 IPR009078; Ferritin-like_SF.
 IPR012348; RNR-rel. 

Pfam

 PF03405; FA_desaturase_2 

SMART

  

PROSITE

  

PRINTS