CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033015
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 3-oxoacyl-[acyl-carrier-protein] synthase, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 OXSM 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
109NEQNFVSKSDIKSMSacetylation[1]
174FQTKGYNKVSPFFVPacetylation[1, 2]
Reference
 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [2] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 220 AA 
Protein Sequence
MSNCLQNFLK ITSTRLLCSR LCQQLRSKRK FFGTVPISRL HRRVVITGIG LVTPLGVGTH 60
LVWDRLIGGE SGIVSLVGEE YKSIPCSVAA YVPRGSDEGQ FNEQNFVSKS DIKSMSSPTI 120
MAIGAAELAM KDSGWHPQSE ADQVATGVAI GMGMIPLEVV SETALNFQTK GYNKVSPFFV 180
PKILVNMAAG QVSIRYKLKG PNHAVSTACT TGAHAVGDSF 220 
Gene Ontology
 GO:0005739; C:mitochondrion; IEA:Compara.
 GO:0016740; F:transferase activity; IEA:UniProtKB-KW. 
Interpro
 IPR018201; Ketoacyl_synth_AS.
 IPR014030; Ketoacyl_synth_N.
 IPR016039; Thiolase-like.
 IPR016038; Thiolase-like_subgr. 
Pfam
 PF00109; ketoacyl-synt 
SMART
  
PROSITE
 PS00606; B_KETOACYL_SYNTHASE 
PRINTS