| Tag | Content |
|---|
| CPLM ID | CPLM-031267 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 |
Protein Synonyms/Alias | cDNA FLJ56883, highly similar to 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 |
Gene Name | PFKFB1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 299 | KYRYRYPKGESYEDL | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | |
Sequence Annotation | |
Keyword | Complete proteome; Kinase; Reference proteome; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 406 AA |
Protein Sequence | MEEKTSRIKV FNLGQYRREA VSYKNYEFFL PDNMEALQIR KQCALAALKD VHNYLSHEEG 60
HVAVFDATNT TRERRSLILQ FAKEHGYKVF FIESICNDPG IIAENIRQVK LGSPDYIDCD 120
REKVLEDFLK RIECYEVNYQ PLDEELDSHL SYIKIFDVGT RYMVNRVQDH IQSRTVYYLM 180
NIHVTPRSIY LCRHGESELN IRGRIGGDSG LSVRGKQYAY ALANFIQSQG ISSLKVWTSH 240
MKRTIQTAEA LGVPYEQWKA LNEIDAGVCE EMTYEEIQEH YPEEFALRDQ DKYRYRYPKG 300
ESYEDLVQRL EPVIMELERQ ENVLVICHQA VMRCLLAYFL DKSSDELPYL KCPLHTVLKL 360
TPVAYGCKVE SIYLNVEAVN THREKPENVD ITREPEEALD TVPAHY 406 |
Gene Ontology | GO:0003873; F:6-phosphofructo-2-kinase activity; IEA:InterPro. GO:0005524; F:ATP binding; IEA:InterPro. GO:0004331; F:fructose-2,6-bisphosphate 2-phosphatase activity; IEA:InterPro. GO:0006003; P:fructose 2,6-bisphosphate metabolic process; IEA:InterPro. GO:0006000; P:fructose metabolic process; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |