UniProt Accession

 F5GZM1_HUMAN; F5GZM1 

Genbank Protein ID

 AC145102; AC147575 

Genbank Nucleotide ID

  

Protein Name

 General transcription factor IIH subunit 2-like protein 

Protein Synonyms/Alias

  

Gene Name

 GTF2H2C 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
240	FCPQCRAKYCELPVE	ubiquitination	[1, 2]
249	CELPVECKICGLTLV	ubiquitination	[1, 2, 3]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 338 AA 

Protein Sequence

Gene Ontology

 GO:0000439; C:core TFIIH complex; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
 GO:0006351; P:transcription, DNA-dependent; IEA:InterPro. 

Interpro

 IPR007198; Ssl1-like.
 IPR004595; TFIIH_C1-like_dom.
 IPR012170; TFIIH_SSL1/p44.
 IPR002035; VWF_A.
 IPR007087; Znf_C2H2. 

Pfam

 PF07975; C1_4
 PF04056; Ssl1 

SMART

 SM01047; C1_4
 SM00327; VWA 

PROSITE

 PS50234; VWFA
 PS00028; ZINC_FINGER_C2H2_1 

PRINTS