CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028684
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MCG54027, isoform CRA_a 
Protein Synonyms/Alias
 [Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial 
Gene Name
 Pdp1 
Gene Synonyms/Alias
 mCG_54027 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
527VDHERLSKMLSLPEEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Hydrolase; Magnesium; Metal-binding; Protein phosphatase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 563 AA 
Protein Sequence
MCVCPGPRRI GIPVRTSSLP LFSDAMPAPT QLFFPLVRNC ELSRIYGTAC YCHHKHLCCS 60
PPYIPQNRLR YTPHPAYATF CRPRENWWQY TQGRRYASTP QKFYLTPPQV NSILKANEYS 120
FKVPEFDGKN VSSILGFDSN QLPANAPIED RRSAATCLQT RGMLLGVFDG HAGCACSQAV 180
SERLFYYIAV SLLPHETLLE IENAVESGRA LLPILQWHKH PNDYFSKEAS KLYFNSLRTY 240
WQELIDLNTG ESADIDVKEA LINAFKRLDN DISLEAQVGD PNSFLNYLVL RVAFSGATAC 300
VAHVDGVDLH VANTGDSRAM LGVQEEDGSW SAVTLSNDHN AQNERELERL KLEHPKNEAK 360
SVVKQDRLLG LLMPFRAFGD VKFKWSIDLQ KRVIESGPDQ LNDNEYTKFI PPNYHTPPYL 420
TAEPEVTYHR LRPQDKFLVL ATDGLWETMH RQDVVRIVGE YLTGMHHQQP IAVGGYKVTL 480
GQMHGLLTER RAKMSSVFED QNAATHLIRH AVGNNEFGAV DHERLSKMLS LPEELARMYR 540
DDITIIVVQF NSHVVGAYQN QEQ 563 
Gene Ontology
 GO:0005739; C:mitochondrion; IDA:MGI.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0004722; F:protein serine/threonine phosphatase activity; IEA:InterPro.
 GO:0035970; P:peptidyl-threonine dephosphorylation; IEA:Compara. 
Interpro
 IPR001932; PP2C-like.
 IPR000222; PP2C_Mn2_Asp60_BS.
 IPR015655; Protein_Pase_2C. 
Pfam
 PF00481; PP2C 
SMART
 SM00331; PP2C_SIG
 SM00332; PP2Cc 
PROSITE
 PS01032; PP2C 
PRINTS