UniProt Accession

 YMY9_YEAST; Q03161; D6VZS2 

Genbank Protein ID

 Z49807; BK006946 

Genbank Nucleotide ID

 CAA89900.1; DAA09996.1 

Protein Name

 Glucose-6-phosphate 1-epimerase 

Protein Synonyms/Alias

 D-hexose-6-phosphate mutarotase 

Gene Name

 YMR099C; YM6543.06C 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
54	AAKLDGSKPVRGGIP	ubiquitination	[1]
69	LVFPVFGKNSTDEHL	acetylation	[2]
78	STDEHLSKLPQHGLA	acetylation	[2]
108	PTVQFGLKPEIANPE	acetylation	[2]
220	RAIQIVDKGVQIHTL	acetylation	[2]
292	LLCKEELKYQAIQ**	ubiquitination	[1]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919] 

Functional Description

 Catalyzes the interconversion between the alpha and beta anomers from at least three hexose 6-phosphate sugars (Glc6P, Gal6P, and Man6P). 

Sequence Annotation

 ACT_SITE 159 159
 ACT_SITE 264 264
 BINDING 57 57 Substrate.
 BINDING 81 81 Substrate.
 BINDING 86 86 Substrate.
 MOD_RES 88 88 Phosphoserine.  

Keyword

 3D-structure; Complete proteome; Isomerase; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 297 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0030246; F:carbohydrate binding; IEA:InterPro.
 GO:0047938; F:glucose-6-phosphate 1-epimerase activity; IDA:SGD.
 GO:0044262; P:cellular carbohydrate metabolic process; IC:SGD. 

Interpro

 IPR008183; Aldose_1/G6P_1-epimerase.
 IPR025532; G6P_1-epimerase.
 IPR011013; Gal_mutarotase_SF_dom.
 IPR014718; Glyco_hydro-type_carb-bd_sub. 

Pfam

 PF01263; Aldose_epim 

SMART

  

PROSITE

  

PRINTS