CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-013101
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Leiomodin-2 
Protein Synonyms/Alias
 Cardiac leiomodin; C-LMOD 
Gene Name
 Lmod2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
467RNIAEVIKQQESAQRubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 May block the elongation and depolymerization of the actin filaments at the pointed end (By similarity). 
Sequence Annotation
 DOMAIN 524 543 WH2.
 REGION 1 42 Tropomyosin-binding.  
Keyword
 Actin-binding; Coiled coil; Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 550 AA 
Protein Sequence
MSTFGYRRGL SKYESIDEDE LLASLSPEEL KELERELEDI EPDRNLPVGL RQKSLTEKTP 60
TGNFSREALM AYWEKESQKL LEKERLGECG KVAEEDKEES EEELIFTESN SEVSEEVCTE 120
DEEESQEEEE DSEEEEDSEE EEETTEATKH INGTVSYNSV NTDNSKPKTF KSQIENINLT 180
NGNSGRTQRN SESPAAIHPC GNPTVIEDAL EKIRNNDPDT TEVNLNNIEN ITTQTLSRFA 240
EALKENTVVK TFSLANTHAD DAAAIAIADM LKVNEHITSV NVESNFITGK GILAIMRALQ 300
HNTVLTELRF HNQRHIMGSQ VEMEIVKLLK ENTTLLRLGY HFELPGPRMS MTSILTRNMD 360
KQRQKRMQEQ KQQEGHDGGA ALRTKVWQRG TPGSSPYASP RQSPWSSPKV SKKVHTGRSR 420
PPSPVAPPPP PPPPPLPPHM LPPPPPPPAP PLPEKKLITR NIAEVIKQQE SAQRALQNGQ 480
RKKKGKKVKK QPNNILKEIK NSLRSVQEKK MEDSSRPSTP QRSVHENLME AIRGSSIRQL 540
RRVEVPEALR 550 
Gene Ontology
 GO:0005856; C:cytoskeleton; IEA:InterPro. 
Interpro
 IPR004934; Tropomodulin. 
Pfam
 PF03250; Tropomodulin 
SMART
  
PROSITE
 PS51082; WH2 
PRINTS