CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029009
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Guanylate binding protein 4.1 
Protein Synonyms/Alias
 Guanylate-binding protein 4 
Gene Name
 Gbp4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
387DENQQFLKKLVELLRubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 631 AA 
Protein Sequence
MTQPQMAPIC LVENHNEQLS VNQEAIEILD KISQPVVVVA IVGWSHTGKS YLMNCLAGQN 60
HVSGTLPTSQ RFPSGLHRAV SDQGHLDVVH APPHQARALV LLDTEGLGDV EKGDPKNDLW 120
IFALSVLLSS TFVYNSMNTI NHQALEQLHY VTELTELIRA KSSPNPHGIK NSTEFVSFFP 180
DFVWTVRDFM LELKLNGEDI TSDEYLENAL KLIPGNNPRI QASNSARECI RRFFPNRKCF 240
VFEWPTHDIE LIKQLETISE DQLDPTFKES AMAFASYIFT YAKIKTLREG IKVTGNGLGT 300
LVTTYVDAIN SGAVPCLDDA VTTLAQRENS VAVQKAASHY SEQMAQRLSL PTDTIQELLD 360
VHAACEKEAM AVFMEHSFKD ENQQFLKKLV ELLREKNGLF LLKNEEASDK YCQEELDRLS 420
KDLMDNISTF SVPGGHRLYM DMREKIEHDY WQVPRKGVKA SEVFQNFLQS QAIIESSILQ 480
ADTALTAGQK AIAEKHTKKE AAEKEQDLLR QKQKEHQEYM EAQEKRNKEN LEQLRRKLEQ 540
EREQLIKDHN MMLEKLTKEQ KTFREEGYKT QAEELRREIH QLGHNIKEMK QNGDSLVESI 600
LRSWFSFISP PSESEKAISS VLSLLRKKDR L 631 
Gene Ontology
 GO:0005525; F:GTP binding; IEA:InterPro.
 GO:0003924; F:GTPase activity; IEA:InterPro.
 GO:0071346; P:cellular response to interferon-gamma; IDA:MGI.
 GO:0006184; P:GTP catabolic process; IEA:GOC.
 GO:0032687; P:negative regulation of interferon-alpha production; IMP:MGI.
 GO:0042308; P:negative regulation of protein import into nucleus; IDA:MGI.
 GO:0001933; P:negative regulation of protein phosphorylation; IDA:MGI.
 GO:0031397; P:negative regulation of protein ubiquitination; IGI:MGI.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IGI:MGI.
 GO:0050688; P:regulation of defense response to virus; IMP:MGI. 
Interpro
 IPR003191; Guanylate-bd_C.
 IPR015894; Guanylate-bd_N.
 IPR027417; P-loop_NTPase. 
Pfam
 PF02263; GBP
 PF02841; GBP_C 
SMART
  
PROSITE
  
PRINTS