UniProt Accession

 ANKY2_HUMAN; Q8IV38; A4D124; Q659G1; Q96BL3 

Genbank Protein ID

 AL050390; CH236948; CH471073; BC015453; BC035353 

Genbank Nucleotide ID

 CAH56419.1; EAL24286.1; EAW93672.1; AAH15453.1; AAH35353.1 

Protein Name

 Ankyrin repeat and MYND domain-containing protein 2 

Protein Synonyms/Alias

  

Gene Name

 ANKMY2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
207	VMDLICEKCMKQRDM	ubiquitination	[1]
366	NLKDIYEKQQLEAAK	ubiquitination	[2]
416	PEDSGEGKKESLESE	ubiquitination	[2]
417	EDSGEGKKESLESEA	ubiquitination	[2]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 

Functional Description

 May be involved in the trafficking of signaling proteins to the cilia (By similarity). 

Sequence Annotation

 REPEAT 45 74 ANK 1.
 REPEAT 79 108 ANK 2.
 REPEAT 159 188 ANK 3.
 ZN_FING 320 357 MYND-type.  

Keyword

 ANK repeat; Cell projection; Cilium; Complete proteome; Metal-binding; Reference proteome; Repeat; Zinc; Zinc-finger. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 441 AA 

Protein Sequence

Gene Ontology

 GO:0005929; C:cilium; IEA:UniProtKB-SubCell.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 

Interpro

 IPR002110; Ankyrin_rpt.
 IPR020683; Ankyrin_rpt-contain_dom.
 IPR002893; Znf_MYND. 

Pfam

 PF12796; Ank_2
 PF01753; zf-MYND 

SMART

 SM00248; ANK 

PROSITE

 PS50297; ANK_REP_REGION
 PS50088; ANK_REPEAT
 PS01360; ZF_MYND_1
 PS50865; ZF_MYND_2 

PRINTS