CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040314
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Angiotensin-converting enzyme 2 
Protein Synonyms/Alias
  
Gene Name
 Ace2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
428DVRVSDLKPRVSFYFacetylation[1]
Reference
 [1] Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.
 Rardin MJ, Newman JC, Held JM, Cusack MP, Sorensen DJ, Li B, Schilling B, Mooney SD, Kahn CR, Verdin E, Gibson BW.
 Proc Natl Acad Sci U S A. 2013 Apr 16;110(16):6601-6. [PMID: 23576753] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 521 AA 
Protein Sequence
MDTYPSYISP TGCLPAHLLG DMWGRFWTNL YPLTVPFAQK PNIDVTDAMM NQGWDAERIF 60
QEAEKFFVSV GLPHMTQGFW ANSMLTEPAD GRKVVCHPTA WDLGHGDFRI KMCTKVTMDN 120
FLTAHHEMGH IQYDMAYARQ PFLLRNGANE GFHEAVGEIM SLSAATPKHL KSIGLLPSDF 180
QEDSETEINF LLKQALTIVG TLPFTYMLEK WRWMVFRGEI PKEQWMKKWW EMKREIVGVV 240
EPLPHDETYC DPASLFHVSN DYSFIRYYTR TIYQFQFQEA LCQAAKYNGS LHKCDISNST 300
EAGQKLLKML SLGNSEPWTK ALENVVGARN MDVKPLLNYF QPLFDWLKEQ NRNSFVGWNT 360
EWSPYADQSI KVRISLKSAL GANAYEWTNN EMFLFRSSVA YAMRKYFSII KNQTVPFLEE 420
DVRVSDLKPR VSFYFFVTSP QNVSDVIPRS EVEDAIRMSR GRINDVFGLN DNSLEFLGIH 480
PTLEPPYQPP VTIWLIIFGV VMALVVVGII ILIVTGIKGR K 521 
Gene Ontology
 GO:0009986; C:cell surface; IEA:Compara.
 GO:0005615; C:extracellular space; IEA:Compara.
 GO:0016020; C:membrane; IEA:Compara.
 GO:0004180; F:carboxypeptidase activity; TAS:MGI.
 GO:0004175; F:endopeptidase activity; IEA:Compara.
 GO:0008237; F:metallopeptidase activity; IEA:InterPro.
 GO:0017046; F:peptide hormone binding; IEA:Compara.
 GO:0008241; F:peptidyl-dipeptidase activity; IEA:InterPro.
 GO:0001618; F:viral receptor activity; IEA:Compara.
 GO:0003051; P:angiotensin-mediated drinking behavior; IEA:Compara.
 GO:0006508; P:proteolysis; IEA:Compara.
 GO:0032800; P:receptor biosynthetic process; IEA:Compara.
 GO:0046813; P:virion attachment, binding of host cell surface receptor; IEA:Compara. 
Interpro
 IPR001548; Peptidase_M2. 
Pfam
 PF01401; Peptidase_M2 
SMART
  
PROSITE
  
PRINTS
 PR00791; PEPDIPTASEA.