CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003718
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Solute carrier family 35 member E2B 
Protein Synonyms/Alias
  
Gene Name
 SLC35E2B 
Gene Synonyms/Alias
 KIAA0447 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
6**MSSSVKTPALEELubiquitination[1]
20LVPGSEEKPKGRSPLubiquitination[1, 2]
22PGSEEKPKGRSPLSWubiquitination[1]
39LFGHRSEKIVFAKSDubiquitination[1, 2]
133PCCLYQHKARLSYPPubiquitination[1]
250KKLLSGDKYRFSAPEubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [2] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302
Functional Description
 Putative transporter (By similarity). 
Sequence Annotation
  
Keyword
 Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 405 AA 
Protein Sequence
MSSSVKTPAL EELVPGSEEK PKGRSPLSWG SLFGHRSEKI VFAKSDGGTD ENVLTVTITE 60
TTVIESDLGV WSSRALLYLT LWFFFSFCTL FLNKYILSLL GGEPSMLGAV QMLSTTVIGC 120
VKTLVPCCLY QHKARLSYPP NFLMTMLFVG LMRFATVVLG LVSLKNVAVS FAETVKSSAP 180
IFTVIMSRMI LGEYTGLLVN LSLIPVMGGL ALCTATEISF NVLGFSAALS TNIMDCLQNV 240
FSKKLLSGDK YRFSAPELQF YTSAAAVAML VPARVFFTDV PVIGRSGKSF SYNQDVVLLL 300
LTDGVLFHLQ SVTAYALMGK ISPVTFSVAS TVKHALSIWL SVIVFGNKIT SLSAVGTALV 360
TVGVLLYNKA RQHQQEALQS LAAATGRAPD DTVEPLLPQD PRQHP 405 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. 
Interpro
 IPR000620; DMT.
 IPR004853; DUF250. 
Pfam
 PF00892; EamA
 PF03151; TPT 
SMART
  
PROSITE
  
PRINTS