CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030892
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Luc7-like protein 3 
Protein Synonyms/Alias
 cDNA FLJ59548, highly similar to Cisplatin resistance-associated overexpressed protein 
Gene Name
 LUC7L3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
48GAAGPTGKNEEKIQVubiquitination[1]
84EEAQGMMKLVEQLKEubiquitination[2, 3]
155KATVEELKEKLRKRTacetylation[3, 4]
155KATVEELKEKLRKRTubiquitination[2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302]
 [4] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 356 AA 
Protein Sequence
MKVGYERDFL RYLQSLLAEV ERRIRRGHAR LALSQNQQSS GAAGPTGKNE EKIQVLTDKI 60
DVLLQQIEEL GSEGKVEEAQ GMMKLVEQLK EERELLRSTT STIESFAAQE KQMEVCEVCG 120
AFLIVGDAQS RVDDHLMGKQ HMGYAKIKAT VEELKEKLRK RTEEPDRDER LKKEKQEREE 180
REKERERERE ERERKRRREE EEREKERARD RERRKRSRSR SRHSSRTSDR RCSRSRDHKR 240
SRSRERRRSR SRDRRRSRSH DRSERKHRSR SRDRRRSKSR DRKSYKHRSK SRDREQDRKS 300
KEKEKRGSDD KKSSVKSGSR EKQSEDTNTE SKESDTKNEV NGTSEDIKSE GLFVTV 356 
Gene Ontology
 GO:0005925; C:focal adhesion; IDA:HPA.
 GO:0005634; C:nucleus; IDA:HPA.
 GO:0005886; C:plasma membrane; IDA:HPA. 
Interpro
 IPR004882; LUC7-rel. 
Pfam
 PF03194; LUC7 
SMART
  
PROSITE
  
PRINTS