CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-042186
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Aspartate aminotransferase 
Protein Synonyms/Alias
  
Gene Name
 Got2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Cavia porcellus (Guinea pig) 
NCBI Taxa ID
 10141 
Lysine Modification
Position
Peptide
Type
References
73AYRDDNGKPYVLPSVacetylation[1]
82YVLPSVRKAEAQLAAacetylation[1]
90AEAQLAAKNVDKEYLacetylation[1]
107AGLAEFCKASAELALacetylation[1]
122GENNEVLKSGRFVTVacetylation[1]
161SRDVYLPKPSWGNHTacetylation[1]
187GYRYYDPKTCGFDFTacetylation[1]
202GAMEDISKIPEQSIIacetylation[1]
229DPRQEQWKEIASVVKacetylation[1]
236KEIASVVKKKNLFAFacetylation[1]
298GAFTVICKDADEAKRacetylation[1]
304CKDADEAKRVESQLKacetylation[1]
311KRVESQLKILIRPMYacetylation[1]
347KQWLQEVKGMADRIIacetylation[1]
365TQLVSNLKKEGSSHNacetylation[1]
389MFCFTGLKPEQVERLacetylation[1]
398EQVERLTKEFSIYMTacetylation[1]
406EFSIYMTKDGRISVAacetylation[1]
432HAIHQVTK*******acetylation[1]
Reference
 [1] The cardiac acetyl-lysine proteome.
 Foster DB, Liu T, Rucker J, O'Meally RN, Devine LR, Cole RN, O'Rourke B.
 PLoS One. 2013;8(7):e67513. [PMID: 23844019
Functional Description
  
Sequence Annotation
  
Keyword
 Aminotransferase; Complete proteome; Pyridoxal phosphate; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 432 AA 
Protein Sequence
MALLHSSRVL SGVAAAFHPG LAAVASARAS SWWTHVEMGP PDPILGVTEA YKRDTNSKKM 60
NLGVGAYRDD NGKPYVLPSV RKAEAQLAAK NVDKEYLPIA GLAEFCKASA ELALGENNEV 120
LKSGRFVTVQ TISGTGALRI GANFLLTPFY KKFSRDVYLP KPSWGNHTPI FRDAGMQLQG 180
YRYYDPKTCG FDFTGAMEDI SKIPEQSIIL LHACAHNPTG VDPRQEQWKE IASVVKKKNL 240
FAFFDMAYQG FASGDGDRDA WAVRHFIEQG INVCLCQSYA KNMGLYGERV GAFTVICKDA 300
DEAKRVESQL KILIRPMYSN PPINGARIAS TILTSPDLRK QWLQEVKGMA DRIISMRTQL 360
VSNLKKEGSS HNWQHITDQI GMFCFTGLKP EQVERLTKEF SIYMTKDGRI SVAGVTSGNV 420
GYLAHAIHQV TK 432 
Gene Ontology
 GO:0005743; C:mitochondrial inner membrane; IEA:Compara.
 GO:0005886; C:plasma membrane; IEA:Compara.
 GO:0004069; F:L-aspartate:2-oxoglutarate aminotransferase activity; IEA:EC.
 GO:0080130; F:L-phenylalanine:2-oxoglutarate aminotransferase activity; IEA:EC.
 GO:0030170; F:pyridoxal phosphate binding; IEA:InterPro.
 GO:0006532; P:aspartate biosynthetic process; IEA:Compara.
 GO:0006533; P:aspartate catabolic process; IEA:Compara.
 GO:0015908; P:fatty acid transport; IEA:Compara.
 GO:0019551; P:glutamate catabolic process to 2-oxoglutarate; IEA:Compara.
 GO:0019550; P:glutamate catabolic process to aspartate; IEA:Compara.
 GO:0006107; P:oxaloacetate metabolic process; IEA:Compara.
 GO:0045471; P:response to ethanol; IEA:Compara. 
Interpro
 IPR004839; Aminotransferase_I/II.
 IPR000796; Asp_trans.
 IPR004838; NHTrfase_class1_PyrdxlP-BS.
 IPR015424; PyrdxlP-dep_Trfase.
 IPR015421; PyrdxlP-dep_Trfase_major_sub1. 
Pfam
 PF00155; Aminotran_1_2 
SMART
  
PROSITE
 PS00105; AA_TRANSFER_CLASS_1 
PRINTS
 PR00799; TRANSAMINASE.