CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-033381
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Lysine-specific demethylase 5D 
Protein Synonyms/Alias
  
Gene Name
 KDM5D 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
130GGYEAICKDRRWARVubiquitination[1]
190EKHPELKKLQIYGPGubiquitination[1]
242NVSSTLLKQHLSLEPubiquitination[1]
315RGIWRCPKCILAECKubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Metal-binding; Nucleus; Reference proteome; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 425 AA 
Protein Sequence
MEPGCDEFLP PPECPVFEPS WAEFQDPLGY IAKIRPIAEK SGICKIRPPA DWQPPFAVEV 60
DNFRFTPRVQ RLNELEAQTR VKLNYLDQIA KFWEIQGSSL KIPNVERKIL DLYSLSKIVI 120
EEGGYEAICK DRRWARVAQR LHYPPGKNIG SLLRSHYERI IYPYEMFQSG ANHVPEPTEE 180
DIEKHPELKK LQIYGPGPKM MGLGLMAKDK DKTVHKKVTC PPTVTVKDEQ SGGGNVSSTL 240
LKQHLSLEPC TKTTMQLRKN HSSAQFIDSY ICQVCSRGDE DDKLLFCDGC DDNYHIFCLL 300
PPLPEIPRGI WRCPKCILAE CKQPPEAFGF EQATQEYSLQ SFGEMADSFK SDYFNMPVHM 360
VPTELVEKEF WRLVSSIEED VTVEYGADIH SKEFGSGFPV SNSKQNLSPE EKEYATSGWN 420
LNVMP 425 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-KW.
 GO:0003677; F:DNA binding; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro. 
Interpro
 IPR001606; ARID/BRIGHT_DNA-bd.
 IPR003349; TF_JmjN.
 IPR019786; Zinc_finger_PHD-type_CS.
 IPR011011; Znf_FYVE_PHD.
 IPR001965; Znf_PHD.
 IPR019787; Znf_PHD-finger.
 IPR013083; Znf_RING/FYVE/PHD. 
Pfam
 PF01388; ARID
 PF02375; JmjN
 PF00628; PHD 
SMART
 SM00501; BRIGHT
 SM00545; JmjN
 SM00249; PHD 
PROSITE
 PS51011; ARID
 PS51183; JMJN
 PS01359; ZF_PHD_1
 PS50016; ZF_PHD_2 
PRINTS