CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-020964
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Transmembrane protein 43 
Protein Synonyms/Alias
 Protein LUMA 
Gene Name
 Tmem43 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
210FKALSLAKLEDPHVDacetylation[1]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 
Functional Description
 May have an important role in maintaining nuclear envelope structure by organizing protein complexes at the inner nuclear membrane. Required for retaining emerin at the inner nuclear membrane. 
Sequence Annotation
 MOD_RES 2 2 N-acetylalanine (By similarity).  
Keyword
 Acetylation; Complete proteome; Endoplasmic reticulum; Membrane; Nucleus; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 400 AA 
Protein Sequence
MAANYSSTSS RKEHVKVTSE PQPGFLERLS ETSGGMFVGL MTFLLSFYLI FTNEGRALKT 60
ATSLAEGLSL VVSPDSIHSV APENEGRLVH IIGALRTSKL LSDPNYGVHL PAVKLRRHVE 120
MYQWVETEES SEYTEDGQVK KETKYSYNTE WRSEIVNSRN FDREIGHKNP SAMAVESFTA 180
TAPFVQIGRF FLSAGLIDKI DNFKALSLAK LEDPHVDIIR RGDFFYHSEN PKYPEVGDVR 240
VSFSYAGLSS DDPDLGPAHV VTVIARQRGD QLIPYSTKSG DTLLLLHHGD FSAEEVFRRE 300
QKSNSMKTWG LRAAGWMAMF MGLNLMTRIL YTLVDWFPVF RDLVNIGLKA FAFCVATSLT 360
LLTVAAGWLF YRPLWAALIG CLALVPIIIA RTRVPAKKLE 400 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-SubCell.
 GO:0005794; C:Golgi apparatus; IEA:Compara.
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005637; C:nuclear inner membrane; IEA:UniProtKB-SubCell. 
Interpro
 IPR012430; TMEM43_fam. 
Pfam
 PF07787; DUF1625 
SMART
  
PROSITE
  
PRINTS