CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041008
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Glutathione peroxidase 
Protein Synonyms/Alias
  
Gene Name
 Gpx4 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
172PGSNQEIKEFAAGYNacetylation[1]
203HPLWKWMKVQPKGRGacetylation[1]
217GMLGNAIKWNFTKFLacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Oxidoreductase; Peroxidase; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 252 AA 
Protein Sequence
MGRAAARKRG RCRQRGRSPG GRRRREPGRQ SPRKRPGPRR RRARARRRRR ARPRRMEPIP 60
EPFNPRPLLQ DLPQTSNSHE FLGLCASRDD WRCARSMHEF AAKDIDGHMV CLDKYRGCVC 120
IVTNVASQGK TDVNYTQLVD LHARYAECGL RILAFPCNQF GRQEPGSNQE IKEFAAGYNV 180
RFDMYSKICV NGDDAHPLWK WMKVQPKGRG MLGNAIKWNF TKFLIDKNGC VVKRYGPMEE 240
PQVIEKDLPC YL 252 
Gene Ontology
 GO:0004602; F:glutathione peroxidase activity; IEA:InterPro.
 GO:0006979; P:response to oxidative stress; IEA:InterPro. 
Interpro
 IPR000889; Glutathione_peroxidase.
 IPR012336; Thioredoxin-like_fold. 
Pfam
 PF00255; GSHPx 
SMART
  
PROSITE
 PS00763; GLUTATHIONE_PEROXID_2
 PS51355; GLUTATHIONE_PEROXID_3 
PRINTS
 PR01011; GLUTPROXDASE.