CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044325
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Kinesin heavy chain isoform 5A 
Protein Synonyms/Alias
  
Gene Name
 KIF5A 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
71NLSVHEDKNRVPFVKacetylation[1]
Reference
 [1] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Microtubule; Motor protein; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 943 AA 
Protein Sequence
MAETNNECSI KVLCRFRPLN QAEILRGDKF IPIFQGDDSV VIGVSYFEIY LDKIRDLLDV 60
TKTNLSVHED KNRVPFVKGC TERFVSSPEE ILDVIDEGKS NRHVAVTNMN EHSSRSHSIF 120
LINIKQENME TEQKLSGKLY LVDLAGSEKV SKTGAEGAVL DEAKNINKSL SALGNVISAL 180
AEGTKSYVPY RDSKMTRILQ DSLGGNCRTT MFICCSPSSY NDAETKSTLM FGQRAKTIKN 240
TASVNLELTA EQWKKKYEKE KEKTKAQKET IAKLEAELSR WRNGENVPET ERLAGEEAAL 300
GAELCEETPV NDNSSIVVRI APEERQKYEE EIRRLYKQLD DKDDEINQQS QLIEKLKQQM 360
LDQEELLVST RGDNEKVQRE LSHLQSENDA AKDEVKEVLQ ALEELAVNYD QKSQEVEEKS 420
QQNQLLVDEL SQKVATMLSL ESELQRLQEV SGHQRKRIAE VLNGLMKDLS EFSVIVGNGE 480
IKLPVEISGA IEEEFTVARL YISKIKSEVK SVVKRCRQLE NLQVECHRKM EVTGRELSSC 540
QLLISQHEAK IRSLTEYMQS VELKKRHLEE SYDSLSDELA KLQAQETVHE VALKDKEPDT 600
QDADEVKKAL ELQMESHREA HHRQLARLRD EINEKQKTID ELKDLNQKLQ LELEKLQADY 660
EKLKSEEHEK STKLQELTFL YERHEQSKQD LKGLEETVAR ELQTLHNLRK LFVQDVTTRV 720
KKSAEMEPED SGGIHSQKQK ISFLENNLEQ LTKVHKQLVR DNADLRCELP KLEKRLRATA 780
ERVKALEGAL KEAKEGAMKD KRRYQQEVDR IKEAVRYKSS GKRGHSAQIA KPVRPGHYPA 840
SSPTNPYGTR SPECISYTNS LFQNYQNLYL QATPSSTSDM YFANSCTSSG ATSSGGPLAS 900
YQKANMDNGN ATDINDNRSD LPCGYEAEDQ AKLFPLHQET AAS 943 
Gene Ontology
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0005875; C:microtubule associated complex; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003777; F:microtubule motor activity; IEA:InterPro.
 GO:0007018; P:microtubule-based movement; IEA:InterPro. 
Interpro
 IPR019821; Kinesin_motor_CS.
 IPR001752; Kinesin_motor_dom.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00225; Kinesin 
SMART
 SM00129; KISc 
PROSITE
 PS00411; KINESIN_MOTOR_DOMAIN1
 PS50067; KINESIN_MOTOR_DOMAIN2 
PRINTS
 PR00380; KINESINHEAVY.