CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-017335
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Zinc finger protein 567 
Protein Synonyms/Alias
  
Gene Name
 ZNF567 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
57TKPDVILKLERGEEPubiquitination[1, 2]
86KAEDFLVKFKEHQEKubiquitination[1]
503HRTHTGEKPYECNECubiquitination[2]
Reference
 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
 May be involved in transcriptional regulation. 
Sequence Annotation
 DOMAIN 6 77 KRAB.
 ZN_FING 210 232 C2H2-type 1; degenerate.
 ZN_FING 253 275 C2H2-type 2.
 ZN_FING 281 303 C2H2-type 3.
 ZN_FING 309 331 C2H2-type 4.
 ZN_FING 337 359 C2H2-type 5.
 ZN_FING 365 387 C2H2-type 6.
 ZN_FING 393 415 C2H2-type 7.
 ZN_FING 421 443 C2H2-type 8.
 ZN_FING 449 471 C2H2-type 9.
 ZN_FING 477 499 C2H2-type 10.
 ZN_FING 505 527 C2H2-type 11.
 ZN_FING 533 555 C2H2-type 12.
 ZN_FING 561 583 C2H2-type 13.
 ZN_FING 589 611 C2H2-type 14.
 ZN_FING 617 639 C2H2-type 15.  
Keyword
 Alternative splicing; Complete proteome; DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat; Transcription; Transcription regulation; Zinc; Zinc-finger. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 647 AA 
Protein Sequence
MAQGSVSFND VTVDFTQEEW QHLDHAQKTL YMDVMLENYC HLISVGCHMT KPDVILKLER 60
GEEPWTSFAG HTCLEENWKA EDFLVKFKEH QEKYSRSVVS INHKKLVKEK SKIYEKTFTL 120
GKNPVNSKNL PPEYDTHGRI LKNVSELIIS NLNPARKRLS EYNGYGKSLL STKQETTHPE 180
VKSHNQSARA FSHNEVLMQY QKTETPAQSF GYNDCEKSFL QRGGLITHSR PYKGENPSVY 240
NKKRRATNIE KKHTCNECGK SFCRKSVLIL HQGIHSEEKP YQCHQCGNAF RRKSYLIDHQ 300
RTHTGEKPFV CNECGKSFRL KTALTDHQRT HTGEKSYECL QCRNAFRLKS HLIRHQRTHT 360
GEKPYECNDC GKSFRQKTTL SLHQRIHTGE KPYICKECGK SFHQKANLTV HQRTHTGEKP 420
YICNECGKSF SQKTTLALHE KTHNEEKPYI CSECGKSFRQ KTTLVAHQRT HTGEKSYECP 480
HCGKAFRMKS YLIDHHRTHT GEKPYECNEC GKSFSQKTNL NLHQRIHTGE KPYVCNECGK 540
SFRQKATLTV HQKIHTGQKS YECPQCGKAF SRKSYLIHHQ RTHTGEKPYK CSECGKCFRQ 600
KTNLIVHQRT HTGEKPYVCN ECGKSFSYKR NLIVHQRTHK GENIEMQ 647 
Gene Ontology
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0006355; P:regulation of transcription, DNA-dependent; IEA:UniProtKB-KW.
 GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. 
Interpro
 IPR001909; Krueppel-associated_box.
 IPR007087; Znf_C2H2.
 IPR015880; Znf_C2H2-like.
 IPR013087; Znf_C2H2/integrase_DNA-bd. 
Pfam
 PF01352; KRAB 
SMART
 SM00349; KRAB
 SM00355; ZnF_C2H2 
PROSITE
 PS50805; KRAB
 PS00028; ZINC_FINGER_C2H2_1
 PS50157; ZINC_FINGER_C2H2_2 
PRINTS