UniProt Accession

 ACNT2_MOUSE; Q8BGG9; B2D099; Q91XC7 

Genbank Protein ID

 EU564338; AK050308; AK050357; BX537352; BX537352; BC010829 

Genbank Nucleotide ID

 ACB55609.1; BAC34180.1; BAC34207.1; CAM27903.3; CAM27904.1; AAH10829.1 

Protein Name

 Acyl-coenzyme A amino acid N-acyltransferase 2 

Protein Synonyms/Alias

  

Gene Name

 Acnat2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
38	VTIKATVKDENDNVF	ubiquitination	[1]
138	WFVGPGVKREQIQEG	ubiquitination	[1]
305	TTQYLHNKLNSQNIL	ubiquitination	[1]
316	QNILPVEKAQGKILF	ubiquitination	[1]
340	DSKLHAQKAMDRLQR	acetylation	[2]

Reference

 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Calorie restriction and SIRT3 trigger global reprogramming of the mitochondrial protein acetylome.
 Hebert AS, Dittenhafer-Reed KE, Yu W, Bailey DJ, Selen ES, Boersma MD, Carson JJ, Tonelli M, Balloon AJ, Higbee AJ, Westphall MS, Pagliarini DJ, Prolla TA, Assadi-Porter F, Roy S, Denu JM, Coon JJ.
 Mol Cell. 2013 Jan 10;49(1):186-99. [PMID: 23201123] 

Functional Description

 Acyltransferase which efficiently conjugates very long- chain and long-chain fatty acids to taurine. Shows no conjugation activity in the presence of glycine (By similarity). 

Sequence Annotation

 MOTIF 418 420 Microbody targeting signal.
 ACT_SITE 235 235 Charge relay system (By similarity).
 ACT_SITE 329 329 Charge relay system (By similarity).
 ACT_SITE 363 363 Charge relay system (By similarity).  

Keyword

 Acyltransferase; Alternative splicing; Complete proteome; Fatty acid metabolism; Lipid metabolism; Peroxisome; Reference proteome; Transferase. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 420 AA 

Protein Sequence

Gene Ontology

 GO:0005777; C:peroxisome; ISS:UniProtKB.
 GO:0016410; F:N-acyltransferase activity; ISS:UniProtKB.
 GO:0016790; F:thiolester hydrolase activity; IEA:InterPro.
 GO:0006637; P:acyl-CoA metabolic process; IEA:InterPro.
 GO:0006631; P:fatty acid metabolic process; ISS:UniProtKB. 

Interpro

 IPR016662; Acyl-CoA_thioEstase_long-chain.
 IPR014940; BAAT_C.
 IPR006862; Thio_Ohase/aa_AcTrfase. 

Pfam

 PF08840; BAAT_C
 PF04775; Bile_Hydr_Trans 

SMART

  

PROSITE

  

PRINTS