| Tag | Content |
|---|
| CPLM ID | CPLM-007331 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | U3 small nucleolar RNA-associated protein 18 |
Protein Synonyms/Alias | U3 snoRNA-associated protein 18; U three protein 18 |
Gene Name | UTP18 |
Gene Synonyms/Alias | YJL069C; HRE594; J1098 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 134 | DSDDEKIKVPILVTN | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Involved in nucleolar processing of pre-18S ribosomal RNA and ribosome assembly. |
Sequence Annotation | REPEAT 246 285 WD 1.
REPEAT 290 334 WD 2.
REPEAT 463 504 WD 3.
REPEAT 513 554 WD 4.
REPEAT 560 593 WD 5.
MOD_RES 182 182 Phosphoserine.
MOD_RES 184 184 Phosphoserine. |
Keyword | Complete proteome; Nucleus; Phosphoprotein; Reference proteome; Repeat; Ribonucleoprotein; Ribosome biogenesis; rRNA processing; WD repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 594 AA |
Protein Sequence | MTMATTAMNV SVPPPDEEEQ LLAKFVFGDT TDLQENLAKF NADFIFNEQE MDVEDQEDEG 60
SESDNSEEDE AQNGELDHVN NDQLFFVDDG GNEDSQDKNE DTMDVDDEDD SSSDDYSEDS 120
EEAAWIDSDD EKIKVPILVT NKTKKLRTSY NESKINGVHY INRLRSQFEK IYPRPKWVDD 180
ESDSELDDEE DDEEEGSNNV INGDINALTK ILSTTYNYKD TLSNSKLLPP KKLDIVRLKD 240
ANASHPSHSA IQSLSFHPSK PLLLTGGYDK TLRIYHIDGK TNHLVTSLHL VGSPIQTCTF 300
YTSLSNQNQQ NIFTAGRRRY MHSWDLSLEN LTHSQTAKIE KFSRLYGHES TQRSFENFKV 360
AHLQNSQTNS VHGIVLLQGN NGWINILHST SGLWLMGCKI EGVITDFCID YQPISRGKFR 420
TILIAVNAYG EVWEFDLNKN GHVIRRWKDQ GGVGITKIQV GGGTTTTCPA LQISKIKQNR 480
WLAVGSESGF VNLYDRNNAM TSSTPTPVAA LDQLTTTISN LQFSPDGQIL CMASRAVKDA 540
LRLVHLPSCS VFSNWPTSGT PLGKVTSVAF SPSGGLLAVG NEQGKVRLWK LNHY 594 |
Gene Ontology | GO:0034388; C:Pwp2p-containing subcomplex of 90S preribosome; IDA:SGD. GO:0032040; C:small-subunit processome; IDA:SGD. GO:0000480; P:endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD. GO:0000447; P:endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD. GO:0000472; P:endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA); IMP:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |