UniProt Accession

 NUDT8_HUMAN; Q8WV74; Q6ZW59 

Genbank Protein ID

 AK123561; BC018644 

Genbank Nucleotide ID

 BAC85646.1; AAH18644.1 

Protein Name

 Nucleoside diphosphate-linked moiety X motif 8, mitochondrial 

Protein Synonyms/Alias

 Nudix motif 8 

Gene Name

 NUDT8 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
61	SRLTGRHKGDVSFPG	ubiquitination	[1]

Reference

 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 Probably mediates the hydrolysis of some nucleoside diphosphate derivatives (By similarity). 

Sequence Annotation

 DOMAIN 25 172 Nudix hydrolase.
 MOTIF 70 91 Nudix box.
 METAL 85 85 Magnesium or manganese (By similarity).
 METAL 89 89 Magnesium or manganese (By similarity).  

Keyword

 Alternative splicing; Complete proteome; Hydrolase; Magnesium; Manganese; Metal-binding; Mitochondrion; Reference proteome; Transit peptide. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 236 AA 

Protein Sequence

Gene Ontology

 GO:0005739; C:mitochondrion; IEA:UniProtKB-SubCell.
 GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. 

Interpro

 IPR000086; NUDIX_hydrolase_dom.
 IPR015797; NUDIX_hydrolase_dom-like. 

Pfam

 PF00293; NUDIX 

SMART

  

PROSITE

 PS51462; NUDIX
 PS00893; NUDIX_BOX 

PRINTS