CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-026165
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 3-oxoacyl-[acyl-carrier-protein] synthase 2 
Protein Synonyms/Alias
  
Gene Name
 TTHA0413 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) 
NCBI Taxa ID
 300852 
Lysine Modification
Position
Peptide
Type
References
24VGQEAFHKAQLAGKSacetylation[1]
Reference
 [1] Acetylome with structural mapping reveals the significance of lysine acetylation in Thermus thermophilus.
 Okanishi H, Kim K, Masui R, Kuramitsu S.
 J Proteome Res. 2013 Aug 1;. [PMID: 23901841
Functional Description
 Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP (By similarity). 
Sequence Annotation
 REGION 126 127 Citrate binding.
 BINDING 122 122 Citrate.  
Keyword
 3D-structure; Acyltransferase; Complete proteome; Fatty acid biosynthesis; Fatty acid metabolism; Lipid biosynthesis; Lipid metabolism; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 408 AA 
Protein Sequence
MRRVVVTGLG ALTPIGVGQE AFHKAQLAGK SGVRPITRFD ASALPVRIAA EVDVDPGAYL 60
DRKELRRLDR FVQYALIAAQ LALEDAGLKP EDLDPERVGT LVGTGIGGME TWEAQSRVFL 120
ERGPNRISPF FIPMMIANMA SAHIAMRYGF TGPSSTVVTA CATGADALGS ALRMIQLGEA 180
DLVLAGGTEA AITPMAIGAF AVMRALSTRN EEPEKASRPF TLSRDGFVMG EGAGVLVLEA 240
YEHAKKRGAR IYAELVGFGR SADAHHITEP HPEGKGAALA MARALKDAGI APEQVGYINA 300
HGTSTPVGDR AEVLAIKRVF GDHAKRLMVS STKSMIGHLL GAAGAVEAIA TVQALYHGVI 360
PPTINLEDPD PELDLDFVPE PREAKVDYAL SNSFAFGGHN AVLAFKRV 408 
Gene Ontology
 GO:0033817; F:beta-ketoacyl-acyl-carrier-protein synthase II activity; IEA:EC.
 GO:0006633; P:fatty acid biosynthetic process; IEA:UniProtKB-UniPathway. 
Interpro
 IPR017568; 3-oxoacyl-ACP_synth-2.
 IPR018201; Ketoacyl_synth_AS.
 IPR014031; Ketoacyl_synth_C.
 IPR014030; Ketoacyl_synth_N.
 IPR016039; Thiolase-like.
 IPR016038; Thiolase-like_subgr. 
Pfam
 PF00109; ketoacyl-synt
 PF02801; Ketoacyl-synt_C 
SMART
  
PROSITE
 PS00606; B_KETOACYL_SYNTHASE 
PRINTS