CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038821
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 S-methylmethionine--homocysteine S-methyltransferase BHMT2 
Protein Synonyms/Alias
  
Gene Name
 Bhmt2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Rattus norvegicus (Rat) 
NCBI Taxa ID
 10116 
Lysine Modification
Position
Peptide
Type
References
123TSLYKYHKDETRIKNacetylation[1]
129HKDETRIKNIFRLQLacetylation[1]
219WTSLQTMKLMKEGLRacetylation[1]
222LQTMKLMKEGLRDAGacetylation[1]
273ATRWDIQKYAREAYNacetylation[1]
330SGLDMHTKPWIRARAacetylation[1]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 362 AA 
Protein Sequence
MAPAGGPRVK KGILERLDSG EVVVGDGGFL FTLEKRGFVK AGLWTPEAVV EYPSAVRQLH 60
TEFLRAGADV LQTFTFSAAE DRMESKWEAV NAAACDLAQE VADGGAALVA GGICQTSLYK 120
YHKDETRIKN IFRLQLGVFA RKNVDFLIAE YFEHVEEAVW AVEVLREVGA PVATMCIGPE 180
GDMHGVTPGE CAVRLSRAGA NIIGVNCRFG PWTSLQTMKL MKEGLRDAGL QAHLMVQCLG 240
FHTPDCGKGG FVDLPEYPFG LEPRVATRWD IQKYAREAYN LGVRYIGGCC GFEPYHIRAI 300
AEELAPERGF LPPASEKHGI WGSGLDMHTK PWIRARARRE YWETLLPASG RPFCPSLSKP 360
DA 362 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0047150; F:betaine-homocysteine S-methyltransferase activity; IEA:InterPro.
 GO:0008898; F:homocysteine S-methyltransferase activity; IEA:InterPro.
 GO:0008270; F:zinc ion binding; IEA:InterPro.
 GO:0009086; P:methionine biosynthetic process; IEA:InterPro. 
Interpro
 IPR017226; Betaine-hCys_S-MeTrfase_BHMT.
 IPR003726; S_MeTrfase. 
Pfam
 PF02574; S-methyl_trans 
SMART
  
PROSITE
 PS50970; HCY 
PRINTS