CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-023542
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Solute carrier family 2, facilitated glucose transporter member 5 
Protein Synonyms/Alias
 Fructose transporter; Glucose transporter type 5, small intestine; GLUT-5 
Gene Name
 Slc2a5 
Gene Synonyms/Alias
 Glut5 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
487VSDVYPKKEEELGALubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Cytochalasin B-sensitive carrier. Seems to function primarily as a fructose transporter (By similarity). 
Sequence Annotation
 CARBOHYD 50 50 N-linked (GlcNAc...) (Potential).  
Keyword
 Complete proteome; Glycoprotein; Membrane; Reference proteome; Sugar transport; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 501 AA 
Protein Sequence
MEEKHQEETG ELTLVLALAT LIAAFGSSFQ YGYNVAAVNS PSEFMQQFYN DTYYDRNEEN 60
IESFTLTLLW SLTVSMFPFG GFIGSLMVGT LVNKLGRKGA LLFNNIFSIL PAILMGCSQI 120
AQSFELIIIS RLLVGICAGI SSNVVPMYLG ELAPKNLRGA LGVVPQLFIT VGILVAQLFG 180
LRSLLANEDG WPVLLGLTGV PAGLQLLLLP FFPESPRYLL IQKKDEAAAE RALQTLRGWK 240
DVHLEMEEIR KEDEAEKAAG FISVWKLFTM QSLRWQLISM IVLMAGQQLS GVNAIYYYAD 300
QIYLSAGVKS DDVQYVTAGT GAVNVFMTIL TIFVVELWGR RFLLLVGFST CLIACLVLTA 360
ALALQNTISW MPYISIVCVI VYVIGHALGP SPIPALLITE IFLQSSRPAA YMIGGSVHWL 420
SNFTVGLIFP FIQMGLGPYS FIIFATICFL TTIYIFMVVP ETKGRTFIEI NQIFTMKNKV 480
SDVYPKKEEE LGALPHAILE Q 501 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005353; F:fructose transmembrane transporter activity; IEA:InterPro.
 GO:0005355; F:glucose transmembrane transporter activity; IEA:Compara. 
Interpro
 IPR002442; Fru_transpt_5.
 IPR020846; MFS_dom.
 IPR016196; MFS_dom_general_subst_transpt.
 IPR005828; Sub_transporter.
 IPR003663; Sugar/inositol_transpt.
 IPR005829; Sugar_transporter_CS. 
Pfam
 PF00083; Sugar_tr 
SMART
  
PROSITE
 PS50850; MFS
 PS00216; SUGAR_TRANSPORT_1
 PS00217; SUGAR_TRANSPORT_2 
PRINTS
 PR01194; GLUCTRSPORT5.
 PR00171; SUGRTRNSPORT.