CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-005703
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ataxin-10 
Protein Synonyms/Alias
 Brain protein E46; Spinocerebellar ataxia type 10 protein homolog 
Gene Name
 Atxn10 
Gene Synonyms/Alias
 Sca10 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
34RALTALFKEQRNRETubiquitination[1]
55QRVLDILKKSTHAVEubiquitination[1]
237LVEAMYGKLSNQERIubiquitination[1]
262VGEEQLTKDDISIFVubiquitination[1]
288DQCRNVLKLTSEPHTubiquitination[1]
345RVIHEVGKESTNIFSubiquitination[1]
358FSPSDSLKAEGDIEHubiquitination[1]
384LIGNLCYKNKENQDKubiquitination[1]
438QNQDVIAKMEEQGLAubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 Necessary for the survival of cerebellar neurons (By similarity). Induces neuritogenesis by activating the Ras-MAP kinase pathway (By similarity). May play a role in the maintenance of a critical intracellular glycosylation level and homeostasis (By similarity). 
Sequence Annotation
 MOD_RES 12 12 Phosphoserine (By similarity).  
Keyword
 Complete proteome; Cytoplasm; Direct protein sequencing; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 475 AA 
Protein Sequence
MAAPRMPPSR LSGIMVPAPI QDLEALRALT ALFKEQRNRE TAPRTIFQRV LDILKKSTHA 60
VELACRDPSQ VEHLASSLQL ITECFRCLRN ACIECSVNQN SIRNLDTIGV AVDLVLLFRE 120
LRVEQDSLLT AFRCGLQFLG NVASRNEESQ SIVWVHAFPE LFMSCLNHPD KKIVAYCSMI 180
LFTSLNAERM KDLEENLNIA INVIEAHQKH PASEWPFLII SDHFLKSPEL VEAMYGKLSN 240
QERITLLDIV IAKLVGEEQL TKDDISIFVR HAELIANSFM DQCRNVLKLT SEPHTEDKEA 300
LVTIRLLDVL CEMTSNTELL GYLQVFPGLM ERVIDVLRVI HEVGKESTNI FSPSDSLKAE 360
GDIEHMTEGF KSHLIRLIGN LCYKNKENQD KVNELDGIPL ILDSSNIDDN NPFMMQWVVY 420
AVRNLTEDNS QNQDVIAKME EQGLADASLL KKMGFEIEKS GDKLILKSNN DIPPP 475 
Gene Ontology
 GO:0005829; C:cytosol; IEA:Compara.
 GO:0030425; C:dendrite; IEA:Compara.
 GO:0043025; C:neuronal cell body; IEA:Compara.
 GO:0048471; C:perinuclear region of cytoplasm; ISS:UniProtKB.
 GO:0031175; P:neuron projection development; IEA:Compara. 
Interpro
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold.
 IPR019156; Ataxin-10_domain. 
Pfam
 PF09759; Atx10homo_assoc 
SMART
  
PROSITE
  
PRINTS