CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029547
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Chloride channel protein 2 
Protein Synonyms/Alias
  
Gene Name
 Clcn2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
842SVTAQGVKVRPPLASubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 891 AA 
Protein Sequence
MAAATAAAAA AAAAGEGMEP RALQYEQTLM YGRYTQELGA FAKEEAARIR LGGPEPWKGS 60
PSARATPELL EYGQSRCARC RICSVRCHKF LVSRVGEDWI FLVLLGLLMA LVSWAMDYAI 120
AVCLQAQQWM SRGLNTNILL QYLAWVTYPV VLITFSAGFT QILAPQAVGS GIPEMKTILR 180
GVVLKEYLTL KTFVAKVIGL TCALGSGMPL GKEGPFVHIA SMCAALLSKF LSLFGGIYEH 240
ESRNTEMLAA ACAVGVGCCF AAPIGGVLFS IEVTSTFFAV RNYWRGFFAA TFSAFIFRVL 300
AVWNRDEETI TALFKTRFRL DFPFDLQELP AFAVIGIASG FGGALFVYLN RKIVQVMRKQ 360
KTINRFLMRK RLLFPALVTL LISTLTFPPG FGQFMAGQLS QKETLVTLFD NRTWVRQGLV 420
EDLELPSTSQ AWSPPRANVF LTLVIFILMK FWMSALATTI PVPCGAFMPV FVIDGIHTDS 480
STYRIVPGGY AVVGAAALAG AVTHTVSTAV IVFELTGQIA HILPVMIAVI LANAVAQSLQ 540
PSLYDSIIRI KKLPYLPELG WGRHQQYRVR VEDIMVRDVP HVALSCTFRD LRLALHRTKG 600
RMLALVESPE SMILLGSIER SQVVALLGAQ LSPARRRQHM QKLRKAQLSP PSDQESPPSS 660
ETSIRFQVNT EDSGFSGAHG QTHKPLKPAL KRGPSNSTSL QEGTTGNMES AGIALRSLFC 720
GSPPLEATSE LEKSESCDKR KLKRVRISLA SDSDPEAEMS PEEILEWEEQ QLDEPVNFSD 780
CKIDPAPFQL VERTSLHKTH TIFSLLGVDH AYVTSIGRLI GIVTLKELRK AIEGSVTAQG 840
VKVRPPLASF RDSATSSSDT ETTEVHALWG PRSRHGLPRE GTPSDSDDKC Q 891 
Gene Ontology
 GO:0016020; C:membrane; IEA:InterPro.
 GO:0005247; F:voltage-gated chloride channel activity; IMP:MGI.
 GO:0060689; P:cell differentiation involved in salivary gland development; IMP:MGI.
 GO:0060041; P:retina development in camera-type eye; IMP:MGI. 
Interpro
 IPR002244; Cl-channel-2.
 IPR014743; Cl-channel_core.
 IPR001807; Cl-channel_volt-gated.
 IPR000644; Cysta_beta_synth_core. 
Pfam
 PF00571; CBS
 PF00654; Voltage_CLC 
SMART
 SM00116; CBS 
PROSITE
 PS51371; CBS 
PRINTS
 PR00762; CLCHANNEL.
 PR01113; CLCHANNEL2.