CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-007115
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Arginase 
Protein Synonyms/Alias
  
Gene Name
 rocF 
Gene Synonyms/Alias
 BSU40320 
Created Date
 July 27, 2013 
Organism
 Bacillus subtilis (strain 168) 
NCBI Taxa ID
 224308 
Lysine Modification
Position
Peptide
Type
References
293LVESLLGKKLL****acetylation[1]
Reference
 [1] The acetylproteome of Gram-positive model bacterium Bacillus subtilis.
 Kim D, Yu BJ, Kim JA, Lee YJ, Choi SG, Kang S, Pan JG.
 Proteomics. 2013 May;13(10-11):1726-36. [PMID: 23468065
Functional Description
 Involved in the catabolism of arginine. 
Sequence Annotation
 REGION 122 126 Substrate binding (By similarity).
 REGION 133 135 Substrate binding (By similarity).
 METAL 97 97 Manganese 1 (By similarity).
 METAL 120 120 Manganese 1 (By similarity).
 METAL 120 120 Manganese 2 (By similarity).
 METAL 122 122 Manganese 2 (By similarity).
 METAL 124 124 Manganese 1 (By similarity).
 METAL 223 223 Manganese 1 (By similarity).
 METAL 223 223 Manganese 2 (By similarity).
 METAL 225 225 Manganese 2 (By similarity).
 BINDING 176 176 Substrate (By similarity).
 BINDING 268 268 Substrate (By similarity).  
Keyword
 Arginine metabolism; Complete proteome; Hydrolase; Manganese; Metal-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 296 AA 
Protein Sequence
MDKTISVIGM PMDLGQARRG VDMGPSAIRY AHLIERLSDM GYTVEDLGDI PINREKIKND 60
EELKNLNSVL AGNEKLAQKV NKVIEEKKFP LVLGGDHSIA IGTLAGTAKH YDNLGVIWYD 120
AHGDLNTLET SPSGNIHGMP LAVSLGIGHE SLVNLEGYAP KIKPENVVII GARSLDEGER 180
KYIKESGMKV YTMHEIDRLG MTKVIEETLD YLSACDGVHL SLDLDGLDPN DAPGVGTPVV 240
GGISYRESHL AMEMLYDAGI ITSAEFVEVN PILDHKNKTG KTAVELVESL LGKKLL 296 
Gene Ontology
 GO:0004053; F:arginase activity; IDA:UniProtKB.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0006525; P:arginine metabolic process; IDA:UniProtKB.
 GO:0000050; P:urea cycle; IEA:UniProtKB-UniPathway. 
Interpro
 IPR014033; Arginase.
 IPR006035; Ureohydrolase.
 IPR023696; Ureohydrolase_domain.
 IPR020855; Ureohydrolase_Mn_BS. 
Pfam
 PF00491; Arginase 
SMART
  
PROSITE
 PS01053; ARGINASE_1
 PS51409; ARGINASE_2 
PRINTS
 PR00116; ARGINASE.