| Tag | Content |
|---|
| CPLM ID | CPLM-007662 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | DNA repair protein RAD52 homolog |
Protein Synonyms/Alias | |
Gene Name | RAD52 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 411 | HRKSQDMKKRKYDPS | sumoylation | [1] | | 412 | RKSQDMKKRKYDPS* | sumoylation | [1] | | 414 | SQDMKKRKYDPS*** | sumoylation | [1] |
|
Reference | [1] The putative nuclear localization signal of the human RAD52 protein is a potential sumoylation site. Saito K, Kagawa W, Suzuki T, Suzuki H, Yokoyama S, Saitoh H, Tashiro S, Dohmae N, Kurumizaka H. J Biochem. 2010 Jun;147(6):833-42. [ PMID: 20190268] |
Functional Description | Involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase. |
Sequence Annotation | MOD_RES 104 104 Phosphotyrosine; by ABL1.
MOD_RES 199 199 Phosphoserine.
MOD_RES 318 318 Phosphothreonine.
MOD_RES 335 335 Phosphothreonine. |
Keyword | 3D-structure; Complete proteome; DNA damage; DNA recombination; DNA repair; Nucleus; Phosphoprotein; Polymorphism; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 418 AA |
Protein Sequence | MSGTEEAILG GRDSHPAAGG GSVLCFGQCQ YTAEEYQAIQ KALRQRLGPE YISSRMAGGG 60
QKVCYIEGHR VINLANEMFG YNGWAHSITQ QNVDFVDLNN GKFYVGVCAF VRVQLKDGSY 120
HEDVGYGVSE GLKSKALSLE KARKEAVTDG LKRALRSFGN ALGNCILDKD YLRSLNKLPR 180
QLPLEVDLTK AKRQDLEPSV EEARYNSCRP NMALGHPQLQ QVTSPSRPSH AVIPADQDCS 240
SRSLSSSAVE SEATHQRKLR QKQLQQQFRE RMEKQQVRVS TPSAEKSEAA PPAPPVTHST 300
PVTVSEPLLE KDFLAGVTQE LIKTLEDNSE KWAVTPDAGD GVVKPSSRAD PAQTSDTLAL 360
NNQMVTQNRT PHSVCHQKPQ AKSGSWDLQT YSADQRTTGN WESHRKSQDM KKRKYDPS 418 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |